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Table 2 Patient and tumor characteristics

From: RECIST and CHOI criteria in the evaluation of tumor response in patients with metastatic colorectal cancer treated with regorafenib, a prospective multicenter study

 

ITT

N = 55

ITT2

N = 35

n %

n %

Gender

Male

30 (55)

22 (63)

Female

25 (45)

13 (37)

Age

Mean

61

61

SD

10.5

9.4

Range

53–69

51–69

Primary tumor present at baseline

 

16 (29)

12 (34)

ECOG PS

0 vs 1

55 (100)

35 (100)

Stage at initial diagnosis

I

1 (2)

1 (3)

II

2 (4)

0

III

12 (22)

8 (23)

IV

40 (73)

26 (74)

Number of site (s) involved

1

12 (22)

8 (23)

2

20 (36)

15 (43)

>2

23 (42)

12 (34)

Prior therapies received

Fluoropyrimidines

 

55 (100)

35 (100)

Oxaliplatin

 

53 (96)

35 (100)

Irinotecan

 

55 (100)

35 (100)

VEGF inhibitorsa

 

53 (96)

34 (97)

EGFR inhibitorsb

 

27 (49)

20 (57)

  1. Abbreviations: SD Standard deviation, ECOG PS Eastern Cooperative Oncology Group Performance Status, EGFR Epidermal growth factor receptor, VEGF Vascular endothelial growth factor
  2. aVEGF bevacizumab and aflibercept
  3. bEGFR cetuximab and panitumumab