RECIST and CHOI criteria in the evaluation of tumor response in patients with metastatic colorectal cancer treated with regorafenib, a prospective multicenter study

Table 1 summary of the response criteria used in the study

	RECIST 1.1	RECIST 10%	CHOI	mCHOI
Measurement	largest Diameter	largest diameter	largest diameter + attenuation^a	largest diameter + attenuation^a
Responders	Decrease ≥30% of the sum of LD of TL or complete response	Decrease >10% of the sum of LD of TL or complete response	Decrease ≥10% of the sum of LD of TL or ≥ 15% of the mean attenuation of TL	Decrease ≥10% of the sum of LD of TL and ≥ 15% of the mean attenuation of TL
Non responders	Do not meet the responder criteria

^aattenuation in Hounsfield units assessed in a free-hand region of interest drawn about 1 mm inside the lesion boundaries on the CECT section whose largest diameter had been measured
LD largest diameter, TL Target lesions, CECT Contrast enhanced computed tomography

ISSN: 1470-7330