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Table 2 The differences in conventional US and CEUS features among the three subtypes of RCC

From: Contrast-enhanced ultrasound findings of adult renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion: comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma

Features

Xp11.2/TFE3 RCC

(n = 18)

ccRCC

(n = 60)

pRCC

(n = 32)

P value

Xp11.2/TFE3 RCC vs ccRCC

Xp11.2/TFE3 RCC vs pRCC

Echogenicity (%)

   

0.605

0.176

 Hypoechoic

6 (33.3)

28 (46.7)

17 (53.1)

  

 Isoechoic

8 (44.4)

21 (35.0)

13 (40.6)

  

 Hyperechoic

4 (22.2)

11 (18.3)

2 (6.3)

  

Cystic component(%)

   

0.413

0.830

 Present

5 (27.8)

23 (38.3)

8 (25.0)

  

 Absent

13 (72.2)

37 (61.7)

24 (75.0)

  

Calcification (%)

   

< 0.001*

0.009*

 Present

9 (50.0)

4 (6.7)

5 (15.6)

  

 Absent

9 (50.0)

56 (93.3)

27 (84.4)

  

Color flow signal (%)

   

0.087

0.198

 Present

7 (38.9)

37 (61.7)

7 (21.9)

  

 Absent

11 (61.1)

23 (38.3)

25 (78.1)

  

Wash-in(%)

   

0.001*

0.022*

 Slow-in

7 (38.9)

3 (5.0)

23 (71.9)

  

 Simultaneous-in

11 (61.1)

57 (95.0)

9 (28.1)

  

Peak Enhancement (%)

   

< 0.001*

0.004*

 Hypoenhancement

6 (33.3)

3 (5.0)

24 (75.0)

  

 Isoenhancement

10 (55.6)

10 (16.7)

4 (12.5)

  

 Hyperenhancement

2 (11.1)

47 (78.3)

4 (12.5)

  

Homogeneity (%)

   

0.683

0.077

 Homogeneous

6 (33.3)

17 (28.3)

19 (59.4)

  

 Heterogeneous

12 (66.7)

43 (71.7)

13 (40.6)

  

Wash-out (%)

   

0.354

0.602

 Fast- or simultaneous-out

16 (88.9)

45 (75.0)

31 (96.9)

  

 Slow-out

2 (11.1)

15 (25.0)

1 (3.1)

  

Pseudocapsule (%)

   

0.449

0.254

 Present

6 (33.3)

26 (43.3)

16 (50.0)

  

 Absent

12 (66.7)

34 (56.7)

16 (50.0)

  
  1. * Significant value