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Table 1 Comparison between clinical and CT texture with KRAS and EGFR mutation status in lung adenocarcinoma

From: Dual-energy spectral CT characteristics in surgically resected lung adenocarcinoma: comparison between Kirsten rat sarcoma viral oncogene mutations and epidermal growth factor receptor mutations

Characteristics

Total

KRAS

EGFR

P value

No. of patients

72

12

60

 

Age (y)a

56.75 ± 10.13

58.75 ± 7.53

56.35 ± 10.58

0.458

Sex

0.054

 Female

42 (58.3)

4 (33.3)

38 (63.3)

 

 Male

30 (41.7)

8 (66.7)

22 (36.7)

 

Smoking

0.002

 Never smoked

55 (76.4)

4 (33.3)

47 (78.3)

 

 Smoker

17 (23.6)

8 (66.7)

13 (21.7)

 

Location

0.521

 Central

2 (2.8)

0 (0.0)

2 (3.3)

 

 Peripheral

70 (97.2)

12 (100.0)

58 (96.7)

 

T stage

0.066

 T1–2

68 (94.4)

10 (83.3)

58 (96.7)

 

 T3–4

4 (5.6)

2 (16.7)

2 (3.3)

 

N stage

0.702

 N0

47 (65.3)

9 (7.5)

38 (63.3)

 

 N1–2

25 (34.7)

3 (2.5)

22 (36.7)

 

Maximum diameterb

2.89 ± 1.29

3.17 ± 1.38

2.83 ± 1.29

0.666

CT texture feature

0.035

 SN

56 (77.8)

12 (100.0)

44 (73.3)

 

 SSN (PSN and NSN)

16 (22.2)

0 (0.0)

16 (26.7)

 
  1. Note. Values are mean ± standard deviation or number (percentage)
  2. aQuantitative data exhibited normal distribution and T test was applied
  3. bQuantitative data did not exhibit normal distribution and Mann-Whitney U test was applied
  4. P < 0.05 indicates significant difference. Significant P values are in bold
  5. SN solid nodule, SSN Subsolid nodule, NIC Normalized iodine concentration, NWC Normalized water concentration, Slope λ HU the slope of the spectral Hounsfield unit curve, Effective Z effective atomic number