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Table 2 Comparison of HCCs showing a complete response according to mRECIST with complete and incomplete lipiodol retention

From: Lipiodol retention pattern after TACE for HCC is a predictor for local progression in lesions with complete response

 

Incomplete (N = 16)

Complete

(N = 30)

p value+

Serum AFP level (μg /L) ± SD

44 ± 110

93 ± 279

0.50

HCC Size (mm) ± SD

22.9 ± 0.8

22.8 ± 10

0.96

HCC location

  

1.00

 - Left lobe

5 (32%)

10 (33%)

 - Right lobe

11 (68%)

20 (66%)

Capsule appearance

4 (25%)

9 (30%)

0.50

Selective cTACE Treatment

10 (62%)

23 (76%)

0.24

Mean Delivered Dose (mg) ± SD

22 ± 11

26 ± 13

0.54

Embolic agent

   

 - Gelfoam

14 (87%)

26 (86%)

0.22

 - PVA particles

0 (0%)

3 (10%)

 - None

2 (13%)

1 (4%)

CBCT guidance

9 (56%)

17 (56%)

0.61

Local progression*

15 (94%)

10 (30%)

<0.01

Mean delay of local progression (months) ± SD

11.1 ± 2

13.4 ± 3

0.51

  1. *median follow-up of 14 months (range 3.2–35.9 months)
  2. + Chi2 test and t-test were used for analysis of discrete and continuous variables respectively
  3. AFP Alpha-fetoprotein, CBCT Cone beam computed tomography, HCC Hepatocellular carcionoma, PVA Polyvinyl alcohol, SD Standard deviation, cTACE Conventional transarterial chemoembolization
  4. significant differences are bold