Fig. 2

A 43-year-old woman with PCV multicentric Castleman disease. Enhanced computed tomography scan shows multicentric, moderately enhancing, enlarged LNs (arrows) in the bilateral axillae (a), abdomen (b) and pelvis (c). Lung windows (d) of the CT scan shows multiple GGOs (arrow), thin-walled cysts (arrowhead), and scattered subpleural nodules (open arrow) with bronchovascular bundle and interlobular septal thickening. Photomicrograph (e, original magnification, × 200; hematoxylin-eosin [H-E] stain) shows diffuse plasma cell proliferations in the interfollicular tissue. (LN = lymph node; UCD = unicentric Castleman disease; MCD = multicentric Castleman disease; HVV = Hyaline vascular variant; PCV = Plasma cell variant; GGOs = Ground-glass opacities)