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Table 3 Radiological features and immunohistochemistry

From: Prediction for early recurrence of intrahepatic mass-forming cholangiocarcinoma: quantitative magnetic resonance imaging combined with prognostic immunohistochemical markers

 

Non-ER (n = 16)

ER (n = 31)

P value

Shape, No. (%)

  

0.063

 Globular

4 (25.0)

1 (3.2)

 

 Lobulate

3 (18.8)

11 (35.5)

 

 Irregular

9 (56.2)

19 (61.3)

 

Lesion contour, No. (%)

  

0.770

 Well defined

11 (68.8)

24 (77.4)

 

 Infiltrative

5 (31.2)

7 (22.6)

 

Biliary dilation, No. (%)

  

0.609

 Present

7 (43.8)

16 (51.6)

 

 Absent

9 (56.2)

15 (48.4)

 

Capsular retraction, No. (%)

  

0.465

 Present

4 (25.0)

11 (35.5)

 

 Absent

12 (75.0)

20 (64.5)

 

DWI intensity, No. (%)

  

0.744

 Hyperintense

10 (62.5)

17 (54.8)

 

 Target appearance

4 (25.0)

11 (35.5)

 

 Slightly hyperintense

2 (12.5)

3 (9.7)

 

Enhancement pattern, No. (%)

  

0.001*

 Gradual enhancement

7 (43.8)

26 (83.9)

 

 Persistent enhancement

3 (18.8)

5 (16.1)

 

 Wash in and wash out

5 (31.2)

0 (0)

 

 No or minimal enhancement

1 (6.2)

0 (0)

 

EGFR, No. (%)

  

0.859

 Negative

3 (18.8)

8 (25.8)

 

 Positive

13 (81.2)

23 (74.2)

 

P53, No. (%)

  

0.555

 Negative

10 (62.5)

22 (71.0)

 

 Positive

6 (37.5)

9 (29.0)

 

VEGFR, No. (%)

  

0.034*

 Negative

8 (50.0)

5 (16.1)

 

 Positive

8 (50.0)

26 (83.9)

 

Ki67, No. (%)

  

0.313

 Negative

7 (43.8)

9 (29.0)

 

 Positive

9 (56.2)

22 (71.0)

 
  1. Note: ER early recurrence, DWI diffusion weighted image, EGFR epidermal growth factor receptor. VEGFR vascular endothelial growth factor receptor, *, P < 0.05