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Fig. 3 | Cancer Imaging

Fig. 3

From: Radiogenomics of breast cancer using dynamic contrast enhanced MRI and gene expression profiling

Fig. 3

Cell Growth and Death. Associations between gene pathways and radiomic features are depicted via hierarchical clustering. Pathways involved in replication and proliferation that have at least one significant positive (green) or negative (red) association with a radiomic features are included in this diagram. These pathways include the canonical cell cycle, DNA replication, base excision repair, non-homologous end joining, mismatch repair, and homologous recombination. Radiomic features are classified by the six characteristic categories, including size, shape, morphology, enhancement texture, kinetic curve assessment, and enhancement-variance kinetics. The apoptosis pathway was also included for contrast

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