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Table 2 Comparison of non-mono-exponential diffusion-related parameters before and after chemotherapy between responders and non-responders

From: Non-mono-exponential diffusion models for assessing early response of liver metastases to chemotherapy in colorectal Cancer

  Parameters Responders (n = 17) Non-responders (n = 16) P-value
Pre-treatment ADCk (10− 3 mm2/s) 1.41 ± 0.28 1.40 ± 0.47 0.444
K 0.77 ± 0.15 0.90 ± 0.15 0.015
DDC (10−3 mm2/s) 1.15 ± 0.27 1.12 ± 0.46 0.382
α 0.80 ± 0.05 0.78 ± 0.13 0.901
Ds (10−3 mm2/s) 1.34 ± 0.37 1.42 ± 0.54 0.817
σ 0.81 ± 0.18 1.03 ± 0.28 0.041
Post-treatment ADCk (10−3 mm2/s) 1.54 ± 0.34 1.72 ± 0.85 0.657
K 0.76 ± 0.11 0.75 ± 0.20 0.929
DDC (10−3 mm2/s) 1.24 ± 0.26 1.46 ± 0.69 0.817
α 0.78 ± 0.09 0.77 ± 0.09 0.657
Ds (10−3 mm2/s) 1.56 ± 0.37 1.73 ± 0.70 0.845
σ 0.73 ± 0.19 0.81 ± 0.29 0.363
Variation rate ΔADCk (%) 12.61 ± 32.15 23.61 ± 43.74 0.510
ΔK (%) 2.99 ± 26.25 −16.19 ± 18.23 0.021
ΔDDC (%) 13.00 ± 34.94 34.18 ± 48.35 0.276
Δα(%) −2.41 ± 13.65 0.20 ± 11.96 0.986
ΔDs (%) 22.31 ± 33.41 29.00 ± 51.01 0.817
Δσ(%) −8.42 ± 20.20 −20.76 ± 18.49 0.034
  1. ADCk apparent diffusion coefficient from the kurtosis model, DDC distributed diffusion coefficients