Table 3 Univariable Cox regression analysis for associations between clinicopathologic characteristics and OS in the whole study cohort (n = 376)
From: Metabolic tumor burden on postsurgical PET/CT predicts survival of patients with gastric cancer
Variables | Number | HR | 95% CI | P values |
|---|---|---|---|---|
Age (years) | ||||
≥ 50 | 192 (51.1%) | 1.019 | 0.799–1.300 | 0.877 |
< 50a | 184 (48.9%) | 1.000 | ||
Gender | ||||
Men | 180 (47.9%) | 0.993 | 0.778–1.267 | 0.955 |
Womena | 196 (52.1%) | 1.000 | … | … |
Pathological type of primary tumor | ||||
PAC/TAC | 112 (29.8%) | 1.122 | 0.797–1.579 | 0.509 |
PDAC | 180 (47.9%) | 1.115 | 0.815–1.526 | 0.495 |
SRC/MACa | 84 (22.3%) | 1.000 | … | … |
Lauren classifications | ||||
Intestinal | 130 (34.6%) | 1.125 | 0.873–1.451 | 0.363 |
Non-intestinala | 246 (65.4%) | 1.000 | … | … |
T stage of primary tumor | ||||
T1 | 95 (25.3%) | 1.005 | 0.611–1.654 | 0.984 |
T2 | 112 (29.8%) | 1.508 | 0.933–2.437 | 0.094 |
T3 | 133 (35.4%) | 1.515 | 0.946–2.428 | 0.084 |
T4a | 36 (9.6%) | 1.000 | … | … |
Gastrectomy | ||||
Total | 178 (47.3%) | 0.899 | 0.705–1.147 | 0.392 |
Subtotala | 198 (52.7%) | 1.000 | … | … |
Lymphovascular invasion | ||||
Yes | 195 (51.9%) | 1.482 | 1.159–1.895 | 0.002 |
Noa | 181 (48.1%) | 1.000 | … | … |
Clinical restage | ||||
Locoregional recurrence | 140 (37.2%) | 0.968 | 0.725–1.291 | 0.823 |
Distant metastasis | 96 (25.6%) | 0.344 | 0.249–0.476 | < 0.001 |
Nonea | 140 (37.2%) | 1.000 | … | … |
Postsurgical adjuvant treatment | ||||
Yes | 220 (58.5%) | 1.552 | 1.207–1.997 | 0.001 |
Noa | 156 (41.5%) | 1.000 | … | … |
PET finding | ||||
Positive | 236 (62.8%) | 2.850 | 2.161–3.758 | < 0.001 |
Negativea | 140 (37.2%) | 1.000 | … | … |