Skip to main content

Table 1 Characteristics of patients between PET positive and negative groups

From: Metabolic tumor burden on postsurgical PET/CT predicts survival of patients with gastric cancer

Characteristics

All patients

(n = 376)

PET findings

P values

Positive

(n = 236)

Negative

(n = 140)

Age (mean ± SD)

51.1 ± 18.4

51.4 ± 18.1

50.7 ± 18.9

0.734*

Gender

0.827

 Men (%)

180 (47.9%)

114 (48.3%)

66 (47.1%)

 

 Women (%)

196 (52.1%)

122 (51.7%)

74 (52.9%)

 

Pathological type of primary tumor

<  0.001

 PAC/TAC

112 (29.8%)

83 (35.2%)

29 (20.7%)

 

 PDAC

180 (47.9%)

117 (49.6%)

63 (45.0%)

 

 SRC/MAC

84 (22.3%)

36 (15.3%)

48 (34.3%)

 

Lauren classifications

0.020

 Intestinal

130 (34.6%)

92 (39.0%)

38 (27.1%)

 

 Non-intestinal

246 (65.4%)

144 (61.0%)

102 (72.9%)

 

T stage of primary tumor

<  0.001

 T1

95 (25.3%)

37 (15.7%)

58 (41.4%)

 

 T2

112 (29.8%)

75 (31.8%)

37 (26.4%)

 

 T3

133 (35.4%)

101 (42.8%)

32 (22.9%)

 

 T4

36 (9.6%)

23 (9.7%)

13 (9.3%)

 

Gastrectomy

0.484

 Total

178 (47.3%)

115 (48.7%)

63 (45.0%)

 

 Subtotal

198 (52.7%)

121 (51.3%)

77 (55.0%)

 

Lymphovascular invasion

<  0.001

 Yes

195 (51.9%)

146 (61.9%)

49 (35.0%)

 

 No

181 (48.1%)

90 (38.1%)

91 (65.0%)

 

Clinical restage

<  0.001

 Locoregional recurrence

140 (37.2%)

140 (59.3%)

 

 Distant metastasis

96 (25.6%)

96 (40.7%)

 

 None

140 (37.2%)

140 (100%)

 

Postsurgical adjuvant treatment

< 0.001

 Yes

220 (58.5%)

175 (74.2%)

45 (32.1%)

 

 No

156 (41.5%)

61 (25.8%)

95 (67.9%)

 

Intervals between surgery and PET/CT (month)

8.6 ± 4.2

8.3 ± 4.2

9.1 ± 4.1

0.103*

Postsurgical MTBWB on PET/CT

 SUVWBmax

8.9 ± 4.7

 

 MTVWB (cm3)

289.7 ± 256.3

 

 TLGWB (cm3)

1002.1 ± 733.6

 

Median OS (month)

19 (5–60)

16 (5–59)

29 (12–60)

< 0.001

  1. Note. SD standard deviation, PAC papillary adenocarcinoma, TAC tubular adenocarcinoma, PDAC poorly differentiated adenocarcinoma, SRC signet-ring cell carcinoma, MAC mucinous adenocarcinoma, MTB metabolic tumor burden, WB whole body, PET/CT positron emission tomography/computed tomography, SUV standardized uptake value, Max maximum, MTV metabolic tumor volume, TLG total lesion glycolysis, OS overall survival. Data in parentheses are percentages or ranges of corresponding variables. *, Student’s t test; †, Chi square test; ‡, Kaplan-Meier analysis with the log-rank test