Table 2 Variables with statistical significance at univariate analysis and logistic regression

Exon 19 mutation

Age

0.004

0.968(0.946~0.990)

0.005

Entropy

0.016

InterquartileRange

0.004

Kurtosis

0.011

MeanAbsoluteDeviation

0.015

RobustMeanAbsoluteDeviation

0.005

StandardDeviation

0.021

Uniformity

0.023

Variance

0.021

ClusterTendency

0.017

Correlation

0.014

DifferenceEntropy

0.047

Entropy

0.025

Imc1

0.03

Imc2

0.006

SumEntropy

0.014

SumSquares

0.018

SumVariance

0.017

GrayLevelNonUniformityNormalized

0.008

0.012(0.000~0.352)

0.01

GrayLevelVariance

0.031

RunEntropy

0.026

ShortRunEmphasis

0.06

Exon 21 mutation

age

0.04

1.027(1.003~1.052)

0.025

Smoking status

0.005

Gender

0.004

2.189(1.264~3.791)

0.005

Maximum

0.015

Range

0.02

Autocorrelation

0.048

ClusterProminence

0.06

HighGrayLevelRunEmphasis

0.04

ShortRunHighGrayLevelEmphasis

0.036

GrayLevelNonUniformityNormalized

0.034

GrayLevelVariance

0.039

SizeZoneNonUniformity

0.013

SizeZoneNonUniformityNormalized

0.012

SmallAreaEmphasis

0.014

LeastAxis

0.009

MajorAxis

0.043

Maximum2DDiameterColumn

0.012

0.968(0.946~0.990)

0.005

Maximum2DDiameterRow

0.066

Maximum2DDiameterSlice

0.019

Maximum3DDiameter

0.025

MinorAxis

0.021

SurfaceArea

0.02

SurfaceVolumeRatio

0.011

Volume

0.017

EGFR mutation

Gender

0.00016

1.883(1.064~3.329)

0.030

Smoking status

0.00015

2.070(1.090~3.929)

0.026

SizeZoneNonUniformityNormalized

0.026

0.010(0.0001~0.852)

0.042

SmallAreaEmphasis

0.037