Table 1 The demographic and pathological characteristics for non-pCR and pCR group
Variables | pCR (n = 40) | non-pCR (n = 102) | P-value |
|---|---|---|---|
Mean age (yrs) | 47.3 ± 11.0 | 43.3 ± 10.0 | 0.10 |
Menopausal status | 0.09 | ||
 Premenopausal | 23(57.5%) | 58(56.9%) |  |
 Postmenopausal | 17(42.5%) | 44(43.1%) |  |
Histologic type | 0.06 | ||
 IDC | 29(72.5%) | 80(78.4%) |  |
 ILC | 11(27.5%) | 22(21.6%) |  |
Clinical stage | 0.03 | ||
 IIa | 8(20.0%) | 9(8.8%) |  |
 IIb | 11(27.5%) | 10(9.8%) |  |
 IIIa | 12(30.0%) | 30(29.4%) |  |
 IIIb | 4(10.0%) | 27(26.5%) |  |
 IIIc | 5(12.5%) | 26(25.5%) |  |
Axillary lymph node metastases | 0.07 | ||
 yes | 17(42.5%) | 32(31.4%) |  |
 no | 23(57.5%) | 70(68.6%) |  |
Cycles of NAC | 0.06 | ||
 4 cycles | 8(20.0%) | 16(15.7%) |  |
 6 cycles | 23(57.5%) | 59(57.8%) |  |
 8 cycles | 9(22.5%) | 27(26.5%) |  |
Surgery | 0.07 | ||
 Breast-conserving surgery | 15(37.5%) | 36(35.3%) |  |
 Modified radical mastectomy | 25(62.5%) | 66(64.7%) |  |
Genomic subtype | 0.04 | ||
 Luminal A | 5(12.5%) | 20(29.4%) |  |
 Luminal B | 14(35.0%) | 30(33.3%) |  |
 Basal-like | 13(32.5%) | 27(15.7%) |  |
 HER2-enriched | 8(20.0%) | 25(23.5%) |  |