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Table 3 Comparison of diagnostic values between PET/CT using the optimized cut-off values and the fixed cut-off value of 2.5 in patients imaged by PET A and B

From: Accuracy of F-18 FDG PET/CT with optimal cut-offs of maximum standardized uptake value according to size for diagnosis of regional lymph node metastasis in patients with rectal cancer

Groups

Cut-off values

Sensitivity (%)

Specificity (%)

PPVa (%)

NPVb (%)

Accuracy (%)

AUCc

p

PET A

 Overall

2.5

36.7

98.0

91.7

71.6

74.7

0.673

0.169

Opt

76.7

77.6

67.6

84.4

77.2

0.771

 Small LN

2.5

18.8

100.0

100.0

74.5

75.9

0.594

0.047

1.1

87.5

73.7

58.3

93.3

77.8

0.806

 Large LN

2.5

57.1

90.9

88.9

62.5

72.0

0.740

0.866

2.1

78.6

72.7

78.6

72.7

76.0

0.756

PET B

 Overall

2.5

35.1

96.7

86.7

70.7

73.2

0.659

0.520

Opt

75.7

65.0

57.1

81.3

69.1

0.703

 Small LN

2.5

18.8

100.0

100.0

78.7

79.7

0.594

0.110

1.0

93.8

60.4

44.1

96.7

68.8

0.771

 Large LN

2.5

47.6

83.3

83.3

47.6

60.6

0.655

0.162

1.9

61.9

83.3

86.7

55.6

69.7

0.726

  1. aPPV positive predictive value
  2. bNPV negative predictive value
  3. cAUC area under the curve
  4. dOpt optimal cut-off values of SUVmax