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Table 2 Comparison of the diagnostic values between PET/CT using the cut-off values of SUVmax optimized according to the lymph node (LN) size and the fixed SUVmax cut-off value of 2.5

From: Accuracy of F-18 FDG PET/CT with optimal cut-offs of maximum standardized uptake value according to size for diagnosis of regional lymph node metastasis in patients with rectal cancer

Group

Cut-off values

Sensitivity (%)

Specificity (%)

PPVa (%)

NPVb (%)

Accuracy (%)

AUCc

p

Overall

2.5

35.8

97.2

88.9

71.1

73.9

0.665

0.071

Optd

76.1

74.3

64.6

83.5

75

0.752

Small LN

2.5

18.8

100

100

76.8

78

0.594

0.005

1.1

90.6

70.9

53.7

95.3

76.3

0.808

Large LN

2.5

51.4

87

85.7

54.1

65.5

0.692

0.429

2.1

68.6

78.3

82.8

62.1

72.4

0.734

  1. aPPV positive predictive value
  2. bNPV negative predictive value
  3. cAUC area under the curve
  4. dOpt optimal cut-off values of SUVmax (1.1 in the small LN group and 2.1 in the large LN group)