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Table 3 Treatment response evaluation to neoadjuvant chemotherapy using 11C-acetate PET/MRI. Patients 1 and 2 participated in both phases of the trial, underwent PET/MRI before any intervention and secondary PET/MRI was performed after completion of NAC. Patients 3–5 were enrolled after TUR-BT and underwent PET/MRI after completion of NAC. Imaging after NAC prior RC was compared to RC pathology

From: 11C-acetate PET/MRI in bladder cancer staging and treatment response evaluation to neoadjuvant chemotherapy: a prospective multicenter study (ACEBIB trial)

Patient

PET/MRI

RC

Primary tumour

LNM +/−

Primary tumour

LN n tot / n+

1

T0

+

T0

27 / 0

2

T4

+

T2

42 / 3

3a

T0

–

T3

27 / 9

4

T0

–

T0

43 / 0

5

T3

–

T2

36 / 0

    

175 / 12

  1. PET/MRI positron emission tomography – magnetic resonance imaging, RC radical cystectomy, LNM lymph node metastasis (+) = suspicion of presence; (−) = suspicion of absence
  2. aPatient had bilateral hip prostheses which distorted the image quality