Fig. 2

76-year-old woman with chronic lymphocytic leukemia with 11q deletion and unmutated IGHV. a Axial CT images of the chest acquired during arterial phase at the time of initial presentation shows a large anterior mediastinal mass measuring up to 10 cm in its largest dimension with bilateral moderate pleural effusions. b Axial CT image of the chest obtained during arterial phase 4 months after initiating R-CHOP demonstrates significant decrease in size of the anterior mediastinal mass and improvement of bilateral pleural effusion. c Axial CT image of the chest obtained during arterial phase 4 years later demonstrates a new mass in the right sub pectoral region measuring up to 3.5 cm in its largest dimension suspicious for CLL (arrowheads). The lesion was biopsied and was consistent for recurrence of CLL