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Table 2 Mean ADC values (×10−3 mm2/s) and standard deviations (SDs) within each recorded ROI and the homogeneity indices (HI, calculated as the SD/mean ADC of each recorded ROI) of the pancreatic adenocarcinomas obtained with the 6 different-sized ROIs by two independent readers

From: Effect of region of interest size on ADC measurements in pancreatic adenocarcinoma

 

ROI20

ROI46

ROI82

ROI115

ROI152

ROI214

P-value1

ADC

HI

ADC

HI

ADC

HI

ADC

HI

ADC

HI

ADC

HI

 

Reader 1 (1st)

1.46 ± 0.28

0.07 ± 0.04

1.46 ± 0.27

0.11 ± 0.11

1.45 ± 0.27

0.12 ± 0.08

1.48 ± 0.26

0.13 ± 0.10

1.45 ± 0.26

0.14 ± 0.10

1.49 ± 0.25

0.15 ± 0.08

0.40

Reader 1 (2nd)

1.45 ± 0.28

0.07 ± 0.06

1.49 ± 0.25

0.09 ± 0.07

1.49 ± 0.26

0.10 ± 0.06

1.48 ± 0.26

0.12 ± 0.09

1.48 ± 0.25

0.13 ± 0.10

1.46 ± 0.26

0.14 ± 0.09

0.39

Reader 2

1.52 ± 0.27

0.06 ± 0.03

1.54 ± 0.25

0.08 ± 0.06

1.51 ± 0.26

0.10 ± 0.06

1.54 ± 0.29

0.12 ± 0.07

1.51 ± 0.27

0.13 ± 0.07

1.46 ± 0.28

0.15 ± 0.10

0.09

  1. The data are summarized as mean ± SD; ROI region of interest, ADC Apparent diffusion coefficient, HI Homogeneity index
  2. 1One way repeated ANOVA of the mean ADC values from the 6 different-sized ROIs. Reader 1 (1st) and Reader 1 (2nd) represent the first and second measurements of the tumor ADCs from reader 1, respectively