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Table 1 Patient, tumour and treatment characteristics (N = 26)

From: Crizotinib Associated Renal Cysts [CARCs]: incidence and patterns of evolution

Age (median, range)

52 (34-66)

Sex (Female)

42%

Ethnicity

Asian 31%, Caucasian 69%

Smoking status

Never 58%, light (<10-pyHx) 15%, heavy (>10pyHx) 27%

Diagnosis

Stage IV 96%, confirmed Adenocarcinoma 96%. ALK FISH rearranged: 92%.

Crizotinib provision

Trial: 69%, Access scheme: 31%

Crizotinib duration (median, range weeks)

58 (22-240)

Crizotinib as line of treatment

1st 34%, 2nd 31%, 3rd 27%, 4th 0%, 5th 8%.

Best radiological response

PD 0%, SD 12%, PR 73%, CR 15%

  1. PD progressive disease, SD stable disease, PR partial response, CR complete response