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Table 2 Statistical values of 3T-MPMRI and FDG-PET/CT scans in the evaluation of CUP

From: Impact of 3T multiparametric MRI and FDG-PET-CT in the evaluation of occult primary cancer with cervical node metastasis

 

Detection rate % T+/38

T+

F-

Sv %

T-

F+

Sp %

PPV

ACC %

LR

MRI native: T1, T2, STIR

15.8

6

11

35.3

13

8

61.9

0.43

50.0

0.92

DWI

34.2

13

2 + 5a

65.0

14

4

77.8

0.76

71.1

2.95

MRI native sequences + DWI

36.8

14

3

82.4

16

5

76.2

0.74

79.0

3.42

MRI native + CE-T1FS

39.5

15

2

88.2

12

9

57.1

0.63

71.1

2.05

MPMRI

39.5

15

2

88.2

15

6

71.4

0.71

79.0

3.03

PET-CT

44.7

17

1

94.4

13

7

65.0

0.71

79.0

2.69

Overall proved by histology

47.4

18

        
  1. T+ true positive, F- false negative, T-: true negative, F+ false positive, Sv sensitivity, Sp specificity, PPV positive predictive value, LR Likelihood Ratio
  2. ain 5 cases reduced imaging information because of susceptibility artifacts