Fig. 9

Patient with HPV-p16 positive cervical squamous cell carcinoma presents for staging. FDG PET (a) demonstrates subtle uptake in an enlarged right external node (b) which would be difficult to discern without knowledge of the CT findings. Correlation with prior contrast-enhanced CT (c) demonstrates the node has rim enhancement and central necrosis consistent with malignant aetiology. The rim of viable tumour is thin and below the resolution of PET imaging explaining the absence of significant uptake. Integration of CT morphology is critical in this case for accurate interpretation