Fig. 1

FDG-PET images illustrating a metabolic response to 37.5 mg daily sunitinib treatment. Single slice coronal inverted grayscale (a, b) and 21-step color (c, d) FDG-PET images from a patient (ID#6) showing a metabolic response to lower-dose sunitinib in a right upper lobe lung lesion (circles). a, c: Baseline images prior to initiation of therapy with sunitinib. b, d: Follow-up images obtained after 28 days of treatment with lower-dose sunitinib. Circles mark the location of the tumor to distinguish it from the normal cardiac and hepatic uptake