Added value of advanced over conventional magnetic resonance imaging in grading gliomas and other primary brain tumors

Table 3 Odds ratios obtained from the univariate analysis of the magnetic resonance variables with significant differences between low-grade and high-grade tumor groups

Variable	OR	95% CI	Pvalue
Enhancement	55.42	15.58-197.15	<0.0001
Necrosis	23.82	8.43-67.35	<0.0001
Neovascularization	7.80	2.53-24.02	<0.0001
Edema	7.43	3.02-18.26	<0.0001
Hemorrhage	13.85	3.93-48.77	<0.0001
rCBV	1.68	1.23-2.19	<0.0001
rADC	0.05	0.01-0.16	<0.0001
NAA/Cr^a	1.21	1.03-1.42	0.02
Cho/Cr^b	1.05	0.97-1.14	0.22
Lipids	9.80	3.56-26.96	<0.0001

CI, confidence interval; OR, odds ratio; Cho, choline; Cr, creatine; NAA, N-acetyl-aspartate; rADC, relative apparent diffusion coefficient; rCBV, relative cerebral blood volume.
^aTE = 23 ms.
^bTE = 144 ms.

ISSN: 1470-7330