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Table 2 Comparison of perfusion-weighted, diffusion-weighted, and magnetic resonance spectroscopy variables between low-grade and high-grade tumor groups

From: Added value of advanced over conventional magnetic resonance imaging in grading gliomas and other primary brain tumors

  Low-grade tumor High-grade tumor  
Variable n Range Mean SD n Range Mean SD PValue
rCBV 29 0.00-13.61 2.09 3.17 95 0.51-19.18 5.75 4.10 <0.0001
rADC 30 0.81-2.55 1.74 0.44 94 0.43-2.63 1.17 0.38 <0.0001
NAA/Cra 23 0.00-11.73 2.39 3.00 64 0.00-42.26 7.28 9.12 0.005
Cho/Crb 24 0.95-21.43 3.56 5.34 70 0.81-77.46 7.95 14.88 0.008
Lipids 26 N/A N/A N/A 83 N/A N/A N/A <0.0001
NAA/Crb 24 0.00-11.61 1.53 2.28 71 0.00-20.36 1.49 3.15 NS
Cho/Cra 23 0.07-9.30 2.00 2,13 65 0.00-30.15 3.24 4.91 NS
Cho/H2Oa 19 3.02×10−4-5.88×10−3 6.60×10−4 1.29×10−3 63 0.00-6.18×10−3 4.21×10−3 8.03×10−4 NS
NAA/H2Oa 20 0.00-3.28×10−3 6.67×10−4 7.85×10−4 63 0.00-1.73×10−2 1.00×10−3 2.20×10−3 NS
Cho/H2Ob 17 2.10x10−4-3.98×10−3 8.39×10−4 9.00×10−3 64 4.74×10−4-8.27×10−3 8.34×10−4 1.23×10−3 NS
NAA/H2Ob 18 0.00-1.01×10−3 3.12×10−4 2.74×10−3 67 0.00-6.86×10−3 3.98×10−4 1,18×10−3 NS
Lactate 26 N/A N/A N/A 83 N/A N/A N/A NS
  1. Cho, choline; Cr, creatine; NAA, N-acetyl-aspartate; N/A, not available (qualitative variables); NS, not significant; rADC, relative apparent diffusion coefficient; rCBV, relative cerebral blood volume.
  2. aTE = 23 ms.
  3. bTE = 144 ms.