Table 4 Lesion-based analysis: performance comparisons between PET/CT and cePET/CT

Sensitivity (%)

80.54 (76.41–84.10)

91.38 (88.25–93.74)

Specificity (%)

54.45 (47.37–61.36)

50.26 (43.24–57.28)

Positive predictive value (%)

78.99 (74.80–82.63)

79.61 (75.72–83.02)

Negative predictive value (%)

56.83 (49.59–63.79)

73.28 (65.12–80.12)

Positive likelihood ratio

1.77 (1.50–2.09)

1.84 (1.58–2.13)

Negative likelihood ratio

0.36 (0.28–0.45)

0.17 (0.12–0.24)

Diagnostic odds ratio

4.93 (3.39–7.21)

10.63 (6.85–16.84)

Error rate (%)

27.81 (24.36–31.53)

21.78 (18.65–25.26)

Accuracy (%)

72.19 (68.47–75.64)

78.22 (74.74–81.35)

Youden’s index

0.349 (0.352–0.347)

0.416 (0.418–0.414)