Table 3 Patient-based performance comparisons between PET/CT and cePET/CT

Sensitivity (%)

92.79 (86.42–96.30)

98.20 (93.67–99.50)

Specificity (%)

76.92 (67.28–84.38)

76.55 (67.02–84.76)

Positive predictive value (%)

83.06 (75.49–88.65)

83.85 (76.56–89.18)

Negative predictive value (%)

89.74 (81.05–94.71)

97.22 (90.43–99.23)

Positive likelihood ratio

4.02 (2.75–5.88)

4.26 (2.92–6.20)

Negative likelihood ratio

0.09 (0.05–0.18)

0.02 (0.01–0.09)

Diagnostic odds ratio

41.67 (16.96–115.67)

174.43 (41.26–1593.39)

Error rate (%)

14.36 (10.19–19.86)

11.39 (7.71–16.51)

Accuracy (%)

85.64 (80.14–89.81)

88.61 (83.49–92.29)

Youden’s index

0.6972 (0.700–0.6940)

0.7512 (0.7541–0.7483)