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  1. The evolution of Positron Emission Tomography (PET), culminating in the Total-Body PET (TB-PET) system, represents a paradigm shift in medical imaging. This paper explores the transformative role of Artificial...

    Authors: Lalith Kumar Shiyam Sundar, Sebastian Gutschmayer, Marcel Maenle and Thomas Beyer
    Citation: Cancer Imaging 2024 24:51
    Content type: Review Published on:

  2. The preoperative identification of tumor grade in chondrosarcoma (CS) is crucial for devising effective treatment strategies and predicting outcomes. The study aims to build and validate a CT-based radiomics n...

    Authors: Xiaoli Li, Xianglong Shi, Yanmei Wang, Jing Pang, Xia Zhao, Yuchao Xu, Qiyuan Li, Ning Wang, Feng Duan and Pei Nie
    Citation: Cancer Imaging 2024 24:50
    Content type: Research article Published on:

  3. The Vesical Imaging-Reporting and Data System (VI-RADS) has demonstrated effectiveness in predicting muscle invasion in bladder cancer before treatment. The urgent need currently is to evaluate the muscle inva...

    Authors: Xinxin Zhang, Yichen Wang, Yilin Wang, Jie Zhang, Jin Zhang, Lianyu Zhang, Sicong Wang, Jianzhong Shou, Yan Chen and Xinming Zhao
    Citation: Cancer Imaging 2024 24:49
    Content type: Research article Published on:

  4. Ductal Carcinoma In Situ (DCIS) can progress to invasive breast cancer, but most DCIS lesions never will. Therefore, four clinical trials (COMET, LORIS, LORETTA, AND LORD) test whether active surveillance for ...

    Authors: Sena Alaeikhanehshir, Madelon M. Voets, Frederieke H. van Duijnhoven, Esther H. lips, Emma J. Groen, Marja C. J. van Oirsouw, Shelley E. Hwang, Joseph Y. Lo, Jelle Wesseling, Ritse M. Mann and Jonas Teuwen
    Citation: Cancer Imaging 2024 24:48
    Content type: Research article Published on:

  5. To investigate the computed tomography (CT) characteristics of air-containing space and its specific patterns in neoplastic and non-neoplastic ground glass nodules (GGNs) for clarifying their significance in d...

    Authors: Si-zhu Liu, Shi-hai Yang, Min Ye, Bin-jie Fu, Fa-jin Lv and Zhi-gang Chu
    Citation: Cancer Imaging 2024 24:47
    Content type: Research article Published on:

  6. PSMA PET/CT is the most sensitive molecular imaging modality for prostate cancer (PCa), yet much of the developing world has little or no access to PET/CT. [99mTc]Tc-PSMA scintigraphy (PS) is a cheaper and more a...

    Authors: Olumayowa U. Kolade, Anita Brink, Akinwale O. Ayeni, Stuart More and Jennifer Holness
    Citation: Cancer Imaging 2024 24:46
    Content type: Research article Published on:

  7. Risk factors for re-bleeding and death after acute variceal bleeding (AVB) in cirrhotic HCC patients are not fully understood.We aimed to (1) explore how the combination of high-risk esophageal varices, HCC st...

    Authors: Mingyuan Zhao, Binyue Zhang, Jianqiang Shi, Xiaoxian Tang, Hongxia Li, Shengwen Li, Yunfeng Yang, Yi Han, Rong Wang, Jian Xun, Kai Zhang, Xirun Wu and Jiang Zhao
    Citation: Cancer Imaging 2024 24:45
    Content type: Research article Published on:

  8. To create radiomics signatures based on habitat to assess the instant response in lung metastases of colorectal cancer (CRC) after radiofrequency ablation (RFA).

    Authors: Haozhe Huang, Hong Chen, Dezhong Zheng, Chao Chen, Ying Wang, Lichao Xu, Yaohui Wang, Xinhong He, Yuanyuan Yang and Wentao Li
    Citation: Cancer Imaging 2024 24:44
    Content type: Research article Published on:

  9. Automatic segmentation of hepatocellular carcinoma (HCC) on computed tomography (CT) scans is in urgent need to assist diagnosis and radiomics analysis. The aim of this study is to develop a deep learning base...

    Authors: I-Cheng Lee, Yung-Ping Tsai, Yen-Cheng Lin, Ting-Chun Chen, Chia-Heng Yen, Nai-Chi Chiu, Hsuen-En Hwang, Chien-An Liu, Jia-Guan Huang, Rheun-Chuan Lee, Yee Chao, Shinn-Ying Ho and Yi-Hsiang Huang
    Citation: Cancer Imaging 2024 24:43
    Content type: Research article Published on:

  10. Positron Emission Tomography (PET) with combined [18F]-FDG and [11C]-acetate (dual-tracer) is used for the management of hepatocellular carcinoma (HCC) patients, although its prognostic value and underlying molec...

    Authors: Keith Wan Hang Chiu, Kel Vin Tan, Xinxiang Yang, Xiaoqiang Zhu, Jingjing Shi, Chi-Leung Chiang, Lawrence Chan, Yuan Hui, Pek-Lan Khong, Kwan Man and Jason Wing Hon Wong
    Citation: Cancer Imaging 2024 24:42
    Content type: Research article Published on:

  11. Authors: Yae Won Park, Ji Eun Park, Sung Soo Ahn, Kyunghwa Han, NakYoung Kim, Joo Young Oh, Da Hyun Lee, So Yeon Won, Ilah Shin, Ho Sung Kim and Seung-Koo Lee
    Citation: Cancer Imaging 2024 24:41
    Content type: Correction Published on:

    The original article was published in Cancer Imaging 2024 24:32

  12. Low-dose computed tomography (LDCT) has been shown useful in early lung cancer detection. This study aimed to develop a novel deep learning model for detecting pulmonary nodules on chest LDCT images.

    Authors: Chia-Ying Lin, Shu-Mei Guo, Jenn-Jier James Lien, Tzung-Yi Tsai, Yi-Sheng Liu, Chao-Han Lai, I-Lin Hsu, Chao-Chun Chang and Yau-Lin Tseng
    Citation: Cancer Imaging 2024 24:40
    Content type: Research article Published on:

  13. Primary thyroid lymphoma (PTL) is a rare malignant disorder, and ultrasound plays an important role in PTL diagnosis and follow-up surveillance. Prediction of refractory/relapse events in PTL patients is an es...

    Authors: Jiang Ji, Luying Gao, Ruifeng Liu, Xinlong Shi, Liyuan Ma, Aonan Pan, Naishi Li, Chunhao Liu, Xiaoyi Li, Meng Yang, Yu Xia and Yuxin Jiang
    Citation: Cancer Imaging 2024 24:39
    Content type: Research article Published on:

  14. To investigate the diagnostic value of dual-energy computed tomography (DECT) quantitative parameters in the identification of regional lymph node metastasis in pancreatic ductal adenocarcinoma (PDAC).

    Authors: Sheng Li, Dongping Jiang, Linling Jiang, Shumei Yan, Lizhi Liu, Guangying Ruan, Xuhui Zhou and Shuiqing Zhuo
    Citation: Cancer Imaging 2024 24:38
    Content type: Research article Published on:

  15. Cutaneous squamous cell carcinoma (CSCC) has a propensity for perineural spread (PNS) which is associated with poorer treatment outcomes. Immunotherapy is the new standard of care treatment for advanced CSCC r...

    Authors: Karda Cavanagh, Luke S. McLean, Annette M. Lim, Anthony Cardin, Sidney M. Levy and Danny Rischin
    Citation: Cancer Imaging 2024 24:37
    Content type: Research article Published on:

  16. The specific genetic subtypes that gliomas exhibit result in variable clinical courses and the need to involve multidisciplinary teams of neurologists, epileptologists, neurooncologists and neurosurgeons. Curr...

    Authors: Haiqing Fan, Yilin Luo, Fang Gu, Bin Tian, Yongqin Xiong, Guipeng Wu, Xin Nie, Jing Yu, Juan Tong and Xin Liao
    Citation: Cancer Imaging 2024 24:36
    Content type: Review Published on:

  17. This review aimed to assess the predictive value of background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) as an imaging biomarker for pathologic complete response (pCR) after neoa...

    Authors: Xue Li and Fuhua Yan
    Citation: Cancer Imaging 2024 24:35
    Content type: Review Published on:

  18. Pulmonary oligometastases are common in hepatocellular carcinoma (HCC), however, the existing therapeutic options have several limitations. This study aimed to assess the safety and efficacy of microwave ablat...

    Authors: Gang Wang, Zhigang Wei, Feihang Wang, Xiaoying Han, Haipeng Jia, Danyang Zhao, Chunhai Li, Lingxiao Liu, Xia Yang and Xin Ye
    Citation: Cancer Imaging 2024 24:34
    Content type: Research article Published on:

  19. To differentiate benign and malignant solitary pulmonary lesions (SPLs) by amide proton transfer-weighted imaging (APTWI), mono-exponential model DWI (MEM-DWI), stretched exponential model DWI (SEM-DWI), and 18F-...

    Authors: Nan Meng, Chen Song, Jing Sun, Xue Liu, Lei Shen, Yihang Zhou, Bo Dai, Xuan Yu, Yaping Wu, Jianmin Yuan, Yang Yang, Zhe Wang and Meiyun Wang
    Citation: Cancer Imaging 2024 24:33
    Content type: Research article Published on:

  20. To assess whether a deep learning-based system (DLS) with black-blood imaging for brain metastasis (BM) improves the diagnostic workflow in a multi-center setting.

    Authors: Yae Won Park, Ji Eun Park, Sung Soo Ahn, Kyunghwa Han, NakYoung Kim, Joo Young Oh, Da Hyun Lee, So Yeon Won, Ilah Shin, Ho Sung Kim and Seung-Koo Lee
    Citation: Cancer Imaging 2024 24:32
    Content type: Research article Published on:

    The Correction to this article has been published in Cancer Imaging 2024 24:41

  21. Identifying breast cancer (BC) patients with germline breast cancer susceptibility gene (gBRCA) mutation is important. The current criteria for germline testing for BC remain controversial. This study aimed to de...

    Authors: Tingting Deng, Jianwen Liang, Cuiju Yan, Mengqian Ni, Huiling Xiang, Chunyan Li, Jinjing Ou, Qingguang Lin, Lixian Liu, Guoxue Tang, Rongzhen Luo, Xin An, Yi Gao and Xi Lin
    Citation: Cancer Imaging 2024 24:31
    Content type: Research article Published on:

  22. Prostate-specific membrane antigen (PSMA) PET/CT imaging is widely used for quantitative image analysis, especially in radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC). Unk...

    Authors: Elmira Yazdani, Najme Karamzadeh-Ziarati, Seyyed Saeid Cheshmi, Mahdi Sadeghi, Parham Geramifar, Habibeh Vosoughi, Mahmood Kazemi Jahromi and Saeed Reza Kheradpisheh
    Citation: Cancer Imaging 2024 24:30
    Content type: Research article Published on:

  23. To investigate the diagnostic value of diffusion kurtosis magnetic resonance imaging (DKI) and conventional diffusion-weighted imaging (DWI) for evaluating the response to first-line chemotherapy in unresectab...

    Authors: Zehua Zhang, Yuqin Zhang, Feixiang Hu, Tiansong Xie, Wei Liu, Huijing Xiang, Xiangxiang Li, Lei Chen and Zhengrong Zhou
    Citation: Cancer Imaging 2024 24:29
    Content type: Research article Published on:

  24. Surgically resected grade 1–2 (G1-2) pancreatic neuroendocrine tumors (PanNETs) exhibit diverse clinical outcomes, highlighting the need for reliable prognostic biomarkers. Our study aimed to develop and valid...

    Authors: Subin Heo, Hyo Jung Park, Hyoung Jung Kim, Jung Hoon Kim, Seo Young Park, Kyung Won Kim, So Yeon Kim, Sang Hyun Choi, Jae Ho Byun, Song Cheol Kim, Hee Sang Hwang and Seung Mo Hong
    Citation: Cancer Imaging 2024 24:28
    Content type: Research article Published on:

  25. The state-of-the-art method for imaging men with biochemical recurrence of prostate cancer (BCR) is prostate-specific membrane antigen (PSMA)-targeted positron emission tomography/computed tomography (PET/CT) ...

    Authors: Florian Rosar, Caroline Burgard, Elena Larsen, Fadi Khreish, Robert J. Marlowe, Andrea Schaefer-Schuler, Stephan Maus, Sven Petto, Mark Bartholomä and Samer Ezziddin
    Citation: Cancer Imaging 2024 24:27
    Content type: Research article Published on:

  26. To investigate the association between Kirsten rat sarcoma viral oncogene homolog (KRAS) / neuroblastoma rat sarcoma viral oncogene homolog (NRAS) /v-raf murine sarcoma viral oncogene homolog B (BRAF) mutation...

    Authors: Hongyue Zhao, Yexin Su, Yan Wang, Zhehao Lyu, Peng Xu, Wenchao Gu, Lin Tian and Peng Fu
    Citation: Cancer Imaging 2024 24:26
    Content type: Research article Published on:

  27. Tumor spread through air spaces (STAS) is associated with poor prognosis and impacts surgical options. We aimed to develop a user-friendly model based on 2-[18F] FDG PET/CT to predict STAS in stage I lung adenoca...

    Authors: Zhaisong Gao, Pingping An, Runze Li, Fengyu Wu, Yuhui Sun, Jie Wu, Guangjie Yang and Zhenguang Wang
    Citation: Cancer Imaging 2024 24:25
    Content type: Research article Published on:

  28. To build machine learning predictive models for surgical risk assessment of extracapsular extension (ECE) in patients with prostate cancer (PCa) before radical prostatectomy; and to compare the use of decision...

    Authors: Adalgisa Guerra, Matthew R. Orton, Helen Wang, Marianna Konidari, Kris Maes, Nickolas K. Papanikolaou and Dow Mu Koh
    Citation: Cancer Imaging 2024 24:24
    Content type: Research article Published on:

  29. The detection of local recurrence for prostate cancer (PCa) patients following radical prostatectomy (RP) is challenging and can influence the treatment plan. Our aim was to construct and verify machine learni...

    Authors: Chenhan Hu, Xiaomeng Qiao, Chunhong Hu, Changhao Cao, Ximing Wang and Jie Bao
    Citation: Cancer Imaging 2024 24:23
    Content type: Research article Published on:

  30. Whole-body magnetic resonance imaging (WB-MRI) has emerged as a valuable tool for cancer detection. This study evaluated the prevalence rates of cancer in asymptomatic individuals undergoing WB-MRI according t...

    Authors: Yong-Sin Hu, Chia-An Wu, Dao-Chen Lin, Po-Wei Lin, Han-Jui Lee, Lo-Yi Lin and Chung-Jung Lin
    Citation: Cancer Imaging 2024 24:22
    Content type: Research article Published on:

  31. I-131 treatment (RAI) decision relies heavily on serum thyroglobulin (Tg) levels, as higher Tg levels are assumed to be correlated with higher I-131 uptake. Tg elevation, negative iodine scintigraphy (TENIS) d...

    Authors: Sang Hyun Hwang, KwanHyeong Jo, Jongtae Cha, Chun Goo Kang, Jiyoung Wang, Hojin Cho, Won Jun Kang and Arthur Cho
    Citation: Cancer Imaging 2024 24:21
    Content type: Research article Published on:

  32. The present study utilized extracted computed tomography radiomics features to classify the gross tumor volume and normal liver tissue in hepatocellular carcinoma by mainstream machine learning methods, aiming...

    Authors: Huai-wen Zhang, De-long Huang, Yi-ren Wang, Hao-shu Zhong and Hao-wen Pang
    Citation: Cancer Imaging 2024 24:20
    Content type: Research article Published on:

  34. Vascular features are not commonly used to evaluate thyroid nodules by conventional ultrasound due to the low sensitivity. Superb Microvascular Imaging (SMI) is a new ultrasonic Doppler technology that special...

    Authors: Wanying Li, Luying Gao, Yiyan Du, Ying Wang, Xiao Yang, Hongyan Wang and Jianchu Li
    Citation: Cancer Imaging 2024 24:18
    Content type: Research article Published on:

  35. American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS, TR) 4 and 5 thyroid nodules (TNs) demonstrate much more complicated and overlapping risk characteristics than TR1-3 and h...

    Authors: Jia-Yu Ren, Wen-Zhi Lv, Liang Wang, Wei Zhang, Ying-Ying Ma, Yong-Zhen Huang, Yue-Xiang Peng, Jian-Jun Lin and Xin-Wu Cui
    Citation: Cancer Imaging 2024 24:17
    Content type: Research article Published on:

  36. More than 40% of patients with resectable esophageal squamous cell cancer (ESCC) achieve pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT), who have favorable prognosis and may be...

    Authors: Yunsong Liu, Yi Wang, Xin Wang, Liyan Xue, Huan Zhang, Zeliang Ma, Heping Deng, Zhaoyang Yang, Xujie Sun, Yu Men, Feng Ye, Kuo Men, Jianjun Qin, Nan Bi, Qifeng Wang and Zhouguang Hui
    Citation: Cancer Imaging 2024 24:16
    Content type: Research article Published on:

  38. Classifying and characterizing pulmonary lesions are critical for clinical decision-making process to identify optimal therapeutic strategies. The purpose of this study was to develop and validate a radiomics ...

    Authors: Jiaxuan Zhou, Yu Wen, Ruolin Ding, Jieqiong Liu, Hanzhen Fang, Xinchun Li, Kangyan Zhao and Qi Wan
    Citation: Cancer Imaging 2024 24:14
    Content type: Research article Published on:

  39. To develop a nomogram using pretreatment ultrasound (US) and contrast-enhanced ultrasound (CEUS) to predict the clinical response of neoadjuvant chemotherapy (NAC) in patients with borderline resectable pancre...

    Authors: Xiaoyi Yan, Xianshui Fu, Yang Gui, Xueqi Chen, Yuejuan Cheng, Menghua Dai, Weibin Wang, Mengsu Xiao, Li Tan, Jing Zhang, Yuming Shao, Huanyu Wang, Xiaoyan Chang and Ke Lv
    Citation: Cancer Imaging 2024 24:13
    Content type: Research article Published on:

  40. Limited data exist on the optimal postoperative surveillance protocol for high-grade soft tissue sarcoma, particularly regarding the optimal imaging modality and imaging interval for detecting local recurrence...

    Authors: Ho Young Park, Hye Won Chung, Min A Yoon, Choong Guen Chee, Wanlim Kim and Jong-Seok Lee
    Citation: Cancer Imaging 2024 24:12
    Content type: Research article Published on:

  41. Esophagectomy is the main treatment for esophageal squamous cell carcinoma (ESCC), and patients with histopathologically negative margins still have a relatively higher recurrence rate. Contrast-enhanced CT (C...

    Authors: Dan Gao, Bang-guo Tan, Xiao-qian Chen, Chuanqinyuan Zhou, Jing Ou, Wen-wen Guo, Hai-ying Zhou, Rui Li, Xiao-ming Zhang and Tian-wu Chen
    Citation: Cancer Imaging 2024 24:11
    Content type: Research article Published on:

  42. To evaluate the effect of Hashimoto’s thyroiditis (HT) on dual-energy computed tomography (DECT) quantitative parameters of cervical lymph nodes (LNs) in patients with papillary thyroid cancer (PTC), and its e...

    Authors: Di Geng, Yan Zhou, Ting Shang, Guo-Yi Su, Shu-shen Lin, Yan Si, Fei-Yun Wu and Xiao-Quan Xu
    Citation: Cancer Imaging 2024 24:10
    Content type: Research article Published on:

  43. The value of bleeding prophylaxis and anticoagulation in patients with hepatocellular carcinoma (HCC) and macrovascular tumour invasion (MVI) is unclear. We evaluated the impact of anticoagulation on thrombosi...

    Authors: Lorenz Balcar, Arpad Mrekva, Bernhard Scheiner, Katharina Pomej, Tobias Meischl, Mattias Mandorfer, Thomas Reiberger, Michael Trauner, Dietmar Tamandl and Matthias Pinter
    Citation: Cancer Imaging 2024 24:9
    Content type: Research article Published on:

  44. In solid-predominantly invasive lung adenocarcinoma (SPILAC), occult lymph node metastasis (OLNM) is pivotal for determining treatment strategies. This study seeks to develop and validate a fusion model combin...

    Authors: Weiwei Tian, Qinqin Yan, Xinyu Huang, Rui Feng, Fei Shan, Daoying Geng and Zhiyong Zhang
    Citation: Cancer Imaging 2024 24:8
    Content type: Research article Published on:

  45. Ultrasound (US) has been widely used in screening and differential diagnosis of gallbladder wall thickening (GWT). However, the sensitivity and specificity for diagnosing wall-thickening type gallbladder cance...

    Authors: Lianhua Zhu, Nan Li, Yaqiong Zhu, Peng Han, Bo Jiang, Miao Li, Yukun Luo, Dirk-André Clevert and Xiang Fei
    Citation: Cancer Imaging 2024 24:7
    Content type: Research article Published on:

  46. To use clinical, radiographic, and CT radiomics features to develop and validate a preoperative prediction model for the early recurrence of pancreatic cancer.

    Authors: Jeong Hyun Lee, Jaeseung Shin, Ji Hye Min, Woo Kyoung Jeong, Honsoul Kim, Seo-Youn Choi, Jisun Lee, Sungjun Hong and Kyunga Kim
    Citation: Cancer Imaging 2024 24:6
    Content type: Research article Published on:

  47. To determine whether histogram analysis based on unenhanced CT can play a role in the differential diagnosis of thymoma and lymphoma from thymic hyperplasia and cyst (mean CT attenuation > 10 HU).

    Authors: Ming Liu, Yang Zhang and Li-Heng Liu
    Citation: Cancer Imaging 2024 24:5
    Content type: Research article Published on:

  48. Percutaneous radiofrequency ablation (RFA) is pivotal for treating small malignant liver tumors, but tumors often remain inconspicuous on B-mode ultrasound (US). This study evaluates the potential of CEUS-CT/M...

    Authors: Yuna Lee, Jeong Hee Yoon, Seungchul Han, Ijin Joo and Jeong Min Lee
    Citation: Cancer Imaging 2024 24:4
    Content type: Research article Published on:

  49. Commercialized total-body PET scanners can provide high-quality images due to its ultra-high sensitivity. We compared the dynamic, regular static, and delayed 18F-fluorodeoxyglucose (FDG) scans to detect lesio...

    Authors: Yaping Wu, Fangfang Fu, Nan Meng, Zhenguo Wang, Xiaochen Li, Yan Bai, Yun Zhou, Dong Liang, Hairong Zheng, Yongfeng Yang, Meiyun Wang and Tao Sun
    Citation: Cancer Imaging 2024 24:2
    Content type: Research article Published on:

  50. Brain metastasis (BM) is most common in non-small cell lung cancer (NSCLC) patients. This study aims to enhance BM risk prediction within three years for advanced NSCLC patients by using a deep learning-based ...

    Authors: Jing Gong, Ting Wang, Zezhou Wang, Xiao Chu, Tingdan Hu, Menglei Li, Weijun Peng, Feng Feng, Tong Tong and Yajia Gu
    Citation: Cancer Imaging 2024 24:1
    Content type: Research article Published on:

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Cancer Imaging

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