Table 1 Baseline characteristics of patients and GGNs
Characteristics | Patients with non-neoplastic GGNs (n = 462) | Patients with neoplastic GGNs (n = 1328) | P-value |
|---|---|---|---|
Mean age (year) (range) | 53.8 ± 11.3 (16 ~ 78) | 55.0 ± 11.4 (22 ~ 88) | 0.041 |
Gender (Male / Female) | 214 (46.3) /248 (53.7) | 422 (31.8) /906 (68.2) | < 0.001 |
Smokers | 95 (20.6) | 303 (22.8) | 0.316 |
Patients with concomitant diseases | |||
Pneumonia | 84 (18.2) | 278 (20.9) | 0.205 |
Bronchiectasis | 37 (8.0) | 92 (6.9) | 0.439 |
Tuberculosis | 7 (1.5) | 16 (1.2) | 0.601 |
Interstitial pneumonia | 10 (2.2) | 43 (3.2) | 0.241 |
Autoimmune diseases | 14 (3.0) | 28 (2.1) | 0.260 |
Cardiac disease | 12 (2.6) | 59 (4.4) | 0.080 |
GGNs | 465 | 1350 | |
Size (mm) (range) | 10.1 ± 4.5 (4 ~ 29) | 11.9 ± 5.2 (4 ~ 29) | < 0.001 |
Location | |||
Right upper lobe | 159 (34.2) | 536 (39.7) | < 0.001 |
Right middle lobe | 28 (6.0) | 88 (6.5) | |
Right inferior lobe | 105 (22.6) | 225 (16.7) | |
Left upper lobe | 104 (22.4) | 363 (26.9) | |
Left inferior lobe | 69 (14.8) | 138 (10.2) | |
Attenuation on CT images | |||
Pure GGN | 190 (41.1) | 684 (50.7) | < 0.001 |
PSN | 274 (58.9) | 666 (49.3) | |
Pathological nature | |||
AAH | / | 95 (7.0) | |
AIS | / | 414 (30.7) | |
MIA | / | 441 (32.7) | |
IAC | / | 400 (29.6) | |
Non-specific inflammation or FIF | 446 (95.9) | / | |
Tuberculosis | 12 (2.6) | / | |
Cryptococcal infection | 3 0.6) | / | |
Focal alveolar hemorrhage | 4 (0.9) | / | |
Surgical procedure | < 0.001 | ||
Wedge resection | 138 (29.7) | 304 (22.5) | |
Segmentectomy | 255 (54.8) | 581 (43.0) | |
Lobectomy | 72 (15.5) | 465 (34.5) |