Habitat-based radiomics analysis for evaluating immediate response in colorectal cancer lung metastases treated by radiofrequency ablation

Table 3 Performance comparison of all signatures

Signature	ACC	AUC	95%CI	Sensitivity	Specificity	PPV	NPV	Youden	Cohort
Clinical	0.777	0.827	0.774–0.879	0.713	0.795	0.483	0.911	0.278	Training
Intra	0.859	0.903	0.867–0.940	0.775	0.882	0.639	0.936	0.252	Training
Peri-5	0.883	0.954	0.934–0.975	0.887	0.882	0.670	0.967	0.236	Training
Peri-10	0.997	0.998	0.995–1.000	0.988	1.000	1.000	0.997	0.375	Training
Habitat	0.748	0.876	0.835–0.917	0.887	0.710	0.452	0.959	0.201	Training
Habitat+Peri-5	0.984	0.994	0.986–1.000	0.950	0.993	0.974	0.987	0.366	Training
Clinical	0.600	0.697	0.564–0.830	0.850	0.541	0.327	0.930	0.193	Test
Intra	0.800	0.769	0.648–0.890	0.650	0.851	0.520	0.900	0.238	Test
Peri-5	0.695	0.825	0.741–0.909	0.950	0.635	0.404	0.979	0.189	Test
Peri-10	0.737	0.816	0.718–0.914	0.850	0.716	0.436	0.946	0.179	Test
Habitat	0.737	0.812	0.721–0.903	0.800	0.730	0.432	0.931	0.212	Test
Habitat + Peri-5	0.853	0.870	0.786–0.954	0.800	0.867	0.615	0.942	0.274	Test

ACC accuracy, AUC the area under the curve, 95%CI 95% confidence interval, PPV positive predictive value, NPV negative predictive value. The bold values mean the best performance of the signature integrating habitat and radiomics features of peritumoral 5 mm

ISSN: 1470-7330