Habitat-based radiomics analysis for evaluating immediate response in colorectal cancer lung metastases treated by radiofrequency ablation

Table 1 Characteristics of patients and CRC lung metastases

Characteristics	Training dataset			Test dataset			P value (N₁ vs N₂)
Characteristics	N₁ = 412	CR = 330	Non-CR = 82	N₂ = 103	CR = 82	Non-CR = 21	P value (N₁ vs N₂)
Age (years)^#	57.91 ± 10.42	57.74 ± 10.37	58.41 ± 10.69	57.48 ± 10.89	58.67 ± 10.81	52.80 ± 9.85	0.59
Gender							0.68
Male	234	184	50	61	48	13
Female	178	146	32	42	34	8
Tumor markers
CEA (ng/ml)^#	14.89 ± 44.12	12.48 ± 37.91	27.13 ± 65.92	13.49 ± 20.80	11.50 ± 16.80	20.84 ± 30.89	0.71
CA19–9 (U/ml)^#	29.73 ± 56.78	25.41 ± 48.32	51.75 ± 88.38	20.67 ± 30.69	18.91 ± 29.86	27.01 ± 32.95	0.29
Lymphadenopathy at diagnosis							0.03
Yes	282	218	64	61	50	11
No	130	112	18	42	32	10
Concomitant systemic treatment							0.10
Yes	276	231	45	59	47	12
No	136	99	37	44	35	9
Initial tumor location							0.60
Rectum	274	216	58	76	57	19
Sigmoid—left colon	58	50	8	11	10	1
Transverse—right colon	75	60	15	14	13	1
Caecum	5	4	1	2	2	0
Nodule size (mm)^#	1.21 ± 0.66	1.12 ± 0.38	1.35 ± 0.42	1.27 ± 0.67	1.20 ± 0.48	1.38 ± 0.71	0.31
Lung metastases location							0.22
RUL	98	87	11	23	19	4
RML	39	32	7	18	16	2
RLL	78	57	21	16	8	8
LUL	94	79	15	22	19	3
LLL	103	75	28	24	20	4
Distance 1							0.28
> 1 cm	340	277	63	79	62	17
< 1 cm	72	53	19	24	20	4
Distance 2							0.08
> 1 cm	161	131	30	49	39	10
< 1 cm	251	199	52	54	43	11
Electrode type							1.00
Expandable	380	310	70	94	76	18
Straight	32	20	12	9	6	3
Pneumothorax							1.00
Yes	115	93	22	28	22	6
No	297	237	60	75	60	15
IAH							0.01
Yes	108	93	15	40	34	6
No	304	237	67	63	48	15

CRC colorectal cancer, CEA carcinoembryonic antigen, CA19–9 cancer antigen 19–9, CR complete response, RUL right upper lobe, RML right middle lobe, RLL right lower lobe, LUL left upper lobe, LLL left lower lobe, Distance 1 the distance between the lesion and the great vessels or mediastinum, Distance 2 the distance between the lesion and the pleura or diaphragm, IAH intra-alveolar hemorrhage
^# Mean ± SD

ISSN: 1470-7330