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Fig. 3 | Cancer Imaging

Fig. 3

From: Prognostic PET [11C]-acetate uptake is associated with hypoxia gene expression in patients with late-stage hepatocellular carcinoma – a bench to bed study

Fig. 3

[11C]-acetate uptake gene signature is prognostic in late stage TCGA HCC patients. (A) GSVA score of genes upregulated in Control versus HAL-treated samples applied to TCGA HCC samples and grouped based on NTP prediction. P-value is calculated using Wilcoxon signed-rank test between the two groups. (B) Kaplan–Meier estimate of NTP group 1 (median OS = 2.22 years) versus group 2 (median OS = 2.23 years) using all TCGA HCC samples (n = 295). (C) Kaplan–Meier estimate of NTP group 1 (median OS = 1.67 years) versus group 2 (median OS = 2.05 years) using only stage III & IV TCGA HCC samples (n = 66)

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Cancer Imaging

ISSN: 1470-7330

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