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Fig. 2 | Cancer Imaging

Fig. 2

From: Prognostic PET [11C]-acetate uptake is associated with hypoxia gene expression in patients with late-stage hepatocellular carcinoma – a bench to bed study

Fig. 2

(A) Volcano plot, (B) Heat map and (C) Gene expression signatures reflect hypoxic state of HAL-treated HCC xenografts. (A) Differential gene expression analysis of Control versus HAL-treated HCC xenografts, (D) GSEA analysis showing enrichment of MSigDB Hallmark pathways in HAL-treated versus Control samples. GSEA plot of genes up (D) and down (E) regulated during hypoxia from Elvidge et al.

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