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Table 1 Characteristics of patients according to the treatment response

From: Radiomics signature for dynamic changes of tumor-infiltrating CD8+ T cells and macrophages in cervical cancer during chemoradiotherapy

Variables

Response

p

PR (n = 13)

CR (n =17)

Age (years)

  

0.177

 <60

10 (76.9%)

9 (52.9%)

 

 ≥60

3 (23.1%)

8 (47.1%)

 

FIGO stage

  

0.030 *

 I~II

4 (30.8%)

12 (70.6%)

 

III~IV

9 (69.2%)

5 (29.4%)

 

Tumor size (cm)

  

0.020 *

 <4

1 (7.7%)

8 (47.1%)

 

 ≥4

12 (92.3%)

9 (52.9%)

 

LNs metastasis

  

0.153

 Negative

5 (38.5%)

11 (64.7%)

 

 Positive

8 (61.5%)

6 (35.3%)

 

Pre-NLR

  

0.009 *

 Low

1 (7.7%)

9 (52.9%)

 

 High

12 (92.3%)

8 (47.1%)

 

Pre-PNR

  

0.225

 Low

9 (69.2%)

8 (47.1%)

 

 High

4 (30.8%)

9 (52.9%)

 

Pre-PLR

  

0.004 *

 Low

4 (30.8%)

14 (82.4%)

 

 High

9 (69.2%)

3 (17.6%)

 

Pre-LMR

  

0.003 *

 Low

7 (53.8%)

1 (5.9%)

 

 High

6 (46.2%)

16 (94.1%)

 

10F-NLR

  

0.127

 Low

4 (30.8%)

10 (58.8%)

 

 High

9 (69.2%)

7 (41.2%)

 

10F-PNR

  

0.012 *

 Low

4 (30.8%)

13 (76.5%)

 

 High

9 (69.2%)

4 (23.5%)

 

10F-PLR

  

0.013 *

 Low

6 (46.2%)

15 (88.2%)

 

 High

7 (53.8%)

2 (11.8%)

 

10F-LMR

  

0.004 *

 Low

10 (76.9%)

4 (23.5%)

 

 High

3 (23.1%)

13 (76.5%)

 

Immune score, median (interquartile range)

0.042 (-0.264 to 0.278)

0.548 (0.416 to 0.749)

0.002 *

  1. Tumor size and LNs metastasis were evaluated by a radiologist according to patient’s MRI before treatment
  2. Abbreviations: LNs metastasis Lymph nodes metastasis, Pre-NLR Neutrophil lymphocyte ratio before treatment, Pre-PNR Platelet neutrophil ratio before treatment, Pre-PLR Platelet lymphocyte ratio before treatment, Pre-LMR Lymphocyte monocyte ratio before treatment, 10F-NLR Neutrophil lymphocyte ratio after 10F RT, 10F-PNR Platelet neutrophil ratio after 10F RT, 10F-PLR Platelet lymphocyte ratio after 10F RT, 10F-LMR Lymphocyte monocyte ratio after 10F RT
  3. Significance: * p value < 0.05