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Table 4 Univariate and multivariate analyses

From: Amide proton transfer-weighted imaging and stretch-exponential model DWI based 18F-FDG PET/MRI for differentiation of benign and malignant solitary pulmonary lesions

Variables

Univariate Analyses

Multivariate Analyses

OR (95% CI)

P-value

OR (95% CI)

P-value

Age (year)

1.447 (0.914 ~ 2.290)

0.115

/

/

Sex

1.158 (0.736 ~ 1.821)

0.526

/

/

Smoking

0.896 (0.566 ~ 1.419)

0.640

/

/

Maximum diameter (mm)

2.279 (1.224 ~ 4.245)

0.009

/

/

SUVmax

9.892 (3.253 ~ 30.082)

 < 0.001

61.636 (5.636 ~ 674.116)

0.001

MTV (ml)

4.330 (1.184 ~ 15.832)

0.027

/

/

TLG (g)

31.119 (2.786 ~ 347.591)

0.005

/

/

ADC (× 10−3mm2/s)

0.128 (0.050 ~ 0.329)

 < 0.001

0.017 (0.002 ~ 0.181)

0.001

DDC (× 10−3mm2/s)

0.406 (0.226 ~ 0.728)

0.002

/

/

α

3.696 (1.816 ~ 7.522)

 < 0.001

/

/

MTRasym(3.5 ppm) (%)

2.085 (1.142 ~ 3.804)

0.017

11.178 (1.378 ~ 90.661)

0.024

  1. Both univariate and multivariate analyses were conducted using the forward LR method
  2. SUVmax Maximum standardized uptake value, MTV Metabolic tumor volume, TLG Total lesion glycolysis, ADC Apparent diffusion coefficient, DDC Distributed diffusion coefficient, α Diffusion heterogeneity index, MTRasym (3.5 ppm) Magnetization transfer ratio asymmetry at 3.5 ppm, OR Odds ratio; *OR for per 1 standard deviation, CI Confidence interval