Skip to main content

Table 3 Comparison of different characteristics between benign and malignant group in the training set

From: Amide proton transfer-weighted imaging and stretch-exponential model DWI based 18F-FDG PET/MRI for differentiation of benign and malignant solitary pulmonary lesions

Variables

Benign group (n = 84)

Malignant group (n = 36)

χ2 / z / t value

P value

Age (year)

57.54 ± 7.98

61.59 ± 11.96

- 1.845

0.069 a

Maximum diameter (mm)

16.50 (9.25, 31.00)

31.50 (24.00, 46.25)

- 3.551

 < 0.001 b

Sex

  

0.404

0.525 c

 Male

16 (57.14%)

36 (64.29%)

  

 Female

12 (42.86%)

20 (35.71%)

  

Smoking

  

0.219

0.640 c

 Never

17 (60.71%)

31 (55.36%)

  

 Always

11 (39.29%)

25 (44.64%)

  

Parameters

 SUVmax

4.38 (2.78, 5.44)

9.63 (6.23, 13.23)

- 5.257

 < 0.001 b

 MTV (ml)

4.05 (2.33, 6.78)

14.46 (4.77, 38.82)

- 3.981

 < 0.001 b

 TLG (g)

6.29 (1.86, 12.96)

62.16 (11.33, 155.71)

- 4.602

 < 0.001 b

 ADC (× 10−3mm2/s)

1.79 ± 0.19

1.42 ± 0.28

7.266

 < 0.001 a

 DDC (× 10−3mm2/s)

3.00 (2.78, 3.32)

1.93 (1.57, 2.60)

- 4.261

 < 0.001 b

 α

0.48 (0.42, 0.52)

0.63 (0.50, 0.78)

- 4.251

 < 0.001 b

 MTRasym(3.5 ppm) (%)

1.07 (0.35, 1.75)

2.58 (0.62, 3.87)

- 2.847

0.004 b

  1. SUVmax Maximum standardized uptake value, MTV Metabolic tumor volume, TLG Total lesion glycolysis, ADC Apparent diffusion coefficient, DDC Distributed diffusion coefficient, α Diffusion heterogeneity index, MTRasym (3.5 ppm) Magnetization transfer ratio asymmetry at 3.5 ppm. A represents the Mann–Whitney U test, b represents the chi-square test and c represents the independent samples t-test