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Table 2 Summary of characteristics in training and testing sets

From: Amide proton transfer-weighted imaging and stretch-exponential model DWI based 18F-FDG PET/MRI for differentiation of benign and malignant solitary pulmonary lesions

Variables

Training set (n = 84)

Test set (n = 36)

χ2 / z / t value

P value

Age (year)

62.50 (54.25, 68.00)

56.00 (51.00, 61.75)

- 2.507

0.012 a

Maximum diameter (mm)

29.50 (18.25, 40.75)

25.00 (16.50, 44.50)

- 0.221

0.825 a

Nature of lesion

  

0.086

0.769

 Benign

28 (33.33%)

13 (36.11%)

  

 Malignant

56 (66.67%)

23 (63.89%)

  

Sex

  

0.007

0.935 b

 Male

52 (61.90%)

22 (61.11%)

  

 Female

32 (38.10%)

14 (38.89%)

  

Smoking

  

1.633

0.201 b

 Never

48 (57.14%)

16 (44.44%)

  

 Always

36 (42.86%)

20 (55.56%)

  

Parameters

 SUVmax

6.76 (4.41, 12.10)

3.66 (2.50, 6.40)

- 3.296

0.001 a

 MTV (ml)

7.87 (3.45, 23.12)

8.55 (2.52, 19.06)

- 1.042

0.297 a

 TLG (g)

20.73 (5.91, 109.11)

17.65 (3.43, 79.45)

- 1.392

0.164 a

 ADCstand (× 10−3mm2/s)

1.54 ± 0.31

1.43 ± 0.29

- 1.898

0.062 c

 DDC (× 10−3mm2/s)

2.41 (1.69, 3.12)

2.29 (1.54, 2.74)

- 0.988

0.323 a

 α

0.53 (0.48, 0.71)

0.62 (0.47, 0.74)

- 0.942

0.346 a

 MTRasym(3.5 ppm) (%)

1.64 (0.51, 3.53)

0.88 (0.40, 3.73)

- 0.793

0.428 a

  1. SUVmax Maximum standardized uptake value, MTV Metabolic tumor volume, TLG Total lesion glycolysis, ADC Apparent diffusion coefficient, DDC Distributed diffusion coefficient, α Diffusion heterogeneity index, MTRasym (3.5 ppm) Magnetization transfer ratio asymmetry at 3.5 ppm. A represents the Mann–Whitney U test, b represents the chi-square test and c represents the independent samples t-test