Table 1 Patient characteristics
Characteristics | gBRCA Mutation (n = 120) | Non-gBRCA Mutation (n = 377) | p |
|---|---|---|---|
Age at diagnosis, year | 41.96 ± 8.58 | 43.60 ± 10.1 | 0.107 |
Tumor size, mm | 26.98 ± 11.0 | 25.86 ± 11.3 | 0.342 |
Menopausal status | Â | Â | 0.743 |
 Postmenopausal | 95 (79.2) | 291 (77.4) |  |
 Premenopausal | 25 (20.8) | 86 (22.8) |  |
Multiple lesions | Â | Â | 0.225 |
 Yes | 10 (8.3) | 49 (13.0) |  |
 No | 110 (91.7) | 328 (87.0) |  |
Bilateral breast cancer | Â | Â | 0.038* |
 Yes | 20 (16.7) | 35 (9.3) |  |
 No | 100 (83.3) | 342 (90.7) |  |
Personal history of breast cancer | Â | Â | 0.009* |
 Yes | 12 (10.0) | 13 (3.4) |  |
 No | 108 (90.0) | 364 (96.6) |  |
Personal history of other BRCA-related cancers | Â | Â | 0.001* |
 Yes | 9 (7.5) | 5 (1.3) |  |
 No | 111 (92.5) | 372 (98.7) |  |
Family history of breast cancer |  |  |  < 0.001* |
 Yes | 47 (39.2) | 73 (19.4) |  |
 No | 73 (60.8) | 304 (80.6) |  |
Family history of other BRCA-related cancers | Â | Â | 0.021* |
 Yes | 12 (10.0) | 15 (4.0) |  |
 No | 108 (90.0) | 362 (96.0) |  |
Histological subtype | Â | Â | 0.110 |
 Invasive | 119 (99.2) | 360 (95.5) |  |
 Non-invasive | 1(0.8) | 17 (4.5) |  |
Grade | Â | Â | 0.756 |
 1 or 2 | 55 (45.8) | 181 (48.0) |  |
 3 | 65 (54.2) | 196 (52.0) |  |
Lymph node status | Â | Â | 0.862 |
 Positive | 60 (50.0) | 194 (51.5) |  |
 Negative | 60 (50.0) | 183 (48.5) |  |
ER status | Â | Â | 0.035* |
 Positive | 73 (60.8) | 270 (71.6) |  |
 Negative | 47 (39.2) | 107 (28.4) |  |
PR status | Â | Â | 0.611 |
 Positive | 72 (60.0) | 238 (63.1) |  |
 Negative | 48 (40.0) | 139 (36.9) |  |
Ki67 | Â | Â | 0.011* |
  ≥ 14% | 115 (95.8) | 328 (87.0) |  |
  < 14% | 5 (4.2) | 49 (13.0) |  |
HER-2 status | Â | Â | 0.005* |
 Positive | 14 (11.7) | 91 (24.1) |  |
 Negative | 106 (88.3) | 286 (75.9) |  |