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Fig. 1 | Cancer Imaging

Fig. 1

From: Value of diffusion kurtosis MR imaging and conventional diffusion weighed imaging for evaluating response to first-line chemotherapy in unresectable pancreatic cancer

Fig. 1

A and E: Axial half-Fourier-acquired single-shot turbo spin echo (HASTE) T2-weighted images; B and F: Diffusion weighted images (DWI) with b-value 0 s/mm2; C and G: Apparent diffusion coefficient (ADC) maps; D and H: Diffusion kurtosis image (DKI) maps. Red arrow: the pancreatic lesion. The images in the first row represent the lesion before undergoing chemotherapy, and the images in the second row represent the lesion that underwent two courses of chemotherapy treatment. Before and after chemotherapy, the ADC and MD values increased significantly, while the MK value decreased slightly. The lesion noticeably shrank after treatment, evaluated as PR according to the RECIST criteria. This patient is a 69-year-old woman with a 4.2 × 3.6 cm mass in the tail of the pancreas and liver metastasis. The following parameters were used: ADCpre (1.06 × 10− 3 mm2/s), ADCpost (1.23 × 10− 3 mm2/s), ADCchange (0.16); MKpre (0.61), MKpost (0.60), MKchange (-0.01); MDpre (1.61 × 10− 3 mm2/s), MDpost (2.58 × 10− 3 mm2/s), MDchange (0.60)

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