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Table 2 Comparison of patient demographic and clinical tumor characteristics between the training cohort and validation cohort

From: Using tumor habitat-derived radiomic analysis during pretreatment 18F-FDG PET for predicting KRAS/NRAS/BRAF mutations in colorectal cancer

Characteristics

Training cohort (n = 37)

Validation cohort (n = 25)

P

Sex

  

0.402a

 Male

26(70.3)

15(60.0)

 

 Female

11(29.7)

10(40.0)

 

Age(year)

64.35 ± 10.71

61.16 ± 10.85

0.257b

Tumor location

  

0.473a

 Colon or sigmoid colon

25(67.6)

19(76.0)

 

 Rectum or rectosigmoid junction

12(32.4)

6(24.0)

 

Differentiation

  

0.933a

 Well/moderate

27(73.0)

18(72.0)

 

 Poor

10(27.0)

7(28.0)

 

TNM stage

  

0.640a

 I-II

17(45.9)

13(52.0)

 

 III-IV

20(54.1)

12(48.0)

 

CEA

  

0.498a

 < 5.0 ng/ml

21(56.8)

12(48.0)

 

 ≥ 5.0 ng/ml

16(43.2)

13(52.0)

 

Mutational status

  

0.953a

 KRAS/NRAS/BRAF mutated

21(56.8)

14(56.0)

 

 Wild type

16(43.2)

11(44.0)

 
  1. CEA carcinoembryonic antigen, KRAS Kirsten rat sarcoma viral oncogene homolog, NRAS neuroblastoma rat sarcoma viral oncogene homolog, BRAF v-raf murine sarcoma viral oncogene homolog B
  2. aChi-square test
  3. bStudent t-tests