Table 2 Patient characteristics and information on brain metastases
Developmental set | Validation set | |||
|---|---|---|---|---|
Site 1 | Site 1 | Site 2 | P-value | |
Number of patients | 101 | 123 | 120 | |
Age | 61.4 ± 9.2 | 65.0 ± 9.7 | 62.6 ± 11.9 | 0.08 |
Male Sex | 60 (59.4) | 68 (55.3) | 72 (60) | 0.42 |
BM Number | 864 | 2078 | 832 | |
Average number of BM for each patient | 8.6 ± 9.6 | 8.7 ± 12.2 | 7.0 ± 6.6 | 0.015 |
Patients with > 10 numbers of BM | 20 (19.8) | 32 (26.0) | 19 (16.8) | 0.050 |
Volume and size (mm3) of BM | ||||
Mean ± SD (volume, mm3) | 204.9 ± 811.8 | 211.5 ± 1406.9 | 345.7 ± 1569.4 | 0.024 |
Mean ± SD (diameter, mm) | 4.69 ± 3.57 | 4.53 ± 3.52 | 4.45 ± 4.55 | 0.625 |
BM numbers less than 5 mm in diameter | 689 (79.5) | 1697 (81.6) | 619 (75.6) | 0.378 |
Primary tumor types | 0.587 | |||
Lung adenocarcinoma | 85 (84.2) | 115 (93.5) | 110 (91.6) | |
Lung squamous cell carcinoma | 5 (4.9) | 8 (6.5) | 10 (8.3) | |
Lung other types of cancer | 2 (1.9) | |||
Breast cancer | 5 (4.9) | |||
Colon cancer | 2 (1.9) | |||
Renal cancer | 4 (1.9) | |||