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Table 2 Univariate and multivariate logistic regression analysis of the independent association between risk factors and STAS

From: Development and validation of a clinic-radiological model to predict tumor spread through air spaces in stage I lung adenocarcinoma

Risk factors

Univariate logistic regression

Multivariate logistic regression

OR

95%CI

P-value

OR

95%CI

P-value

Age ≥ 56 years

3.373

1.265–8.991

0.015*

3.310

1.150–9.530

0.027*

Lesion density subtypea

  

< 0.001**

  

0.004*

    part-solid

2.237

0.604–8.288

0.228

1.165

0.282–4.813

0.833

    solid

13.867

3.960–48.553

< 0.001**

3.268

1.416–7.539

0.043*

Spiculation

3.483

1.796–6.756

< 0.001**

1.452

0.642–3.286

0.371

Bronchial truncation

3.547

1.589–7.919

0.002*

1.485

0.574–3.841

0.415

SUVmax ≥ 2.5 g/ml

7.045

3.492–14.212

< 0.001**

3.268

1.416–7.539

0.005*

  1. STAS tumor spread through air spaces, OR odds ratio, SUVmax the maximum standardized uptake value
  2. *Statistically significant, P < 0.05; **Statistically significant, P < 0.001; aThe pure ground-glass group was considered the reference