Table 1 Data distributions of the clinical and semantic features in the discovery and validation data sets. Binary semantic features have the counts for absent/present, (values in parentheses are percentages), and mean +/ sd is given for continuous features. P-values comparing the discovery and test distributions are computed using Fisher’s exact test for binary features (and PIRADS), and unpaired t-tests are used for continuous features
Feature | Discovery (N = 139) | Test (N = 55) | p-value | |||
|---|---|---|---|---|---|---|
Clinical | Gleason (low/high) | 97/42 | (69.8/30.2) | 33/22 | (60.0/40.0) | 0.24 |
PIRADS (3/4/5) | 6/75/58 | (4.3/54.0/41.7) | 3/33/19 | (5.5/60.0/34.5) | 0.68 | |
PSA | 7.12 +/- 4.02 | 6.97 +/- 5.20 | 0.45 | |||
Major Length Index | 14.3 +/- 5.7 | 14.1 +/- 6.8 | 0.90 | |||
Prostate Volume | 43.0 +/- 21.3 | 48.3 +/- 23.8 | 0.084 | |||
Semantic | Capsular Contact Length | 12.5 +/- 8.8 | 12.8 +/- 11.2 | 0.85 | ||
Smooth Capsular Bulging | 55/84 | (39.6/60.4) | 32/23 | (58.2/41.8) | 0.03 | |
Capsular Disruption | 71/68 | (51.1/48.9) | 34/21 | (61.8/38.2) | 0.20 | |
Unsharp Margin | 64/75 | (46.0/54.0) | 32/23 | (58.2/41.8) | 0.15 | |
Irregular Contour | 80/59 | (57.6/42.4) | 34/21 | (61.8/38.2) | 0.63 | |
Black striation Periprostatic Fat | 110/29 | (79.1/20.9) | 44/11 | (80.0/20.0) | 1.00 | |
Retoprostatic Angle Obliteration | 130/9 | (93.5/6.5) | 49/6 | (89.1/10.9) | 0.37 | |
Baseline | Measurable ECE | 119/20 | (85.6/14.4) | 48/7 | (87.3/12.7) | 1.00 |
Target | Pathological ECE | 103/36 | (74.1/25.9) | 36/19 | (65.5/34.5) | 0.29 |