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Table 5 Univariable and multivariable Firth logistic regression analyses for factors associated with ONCO-RADS ≥ 4

From: Applying ONCO-RADS to whole-body MRI cancer screening in a retrospective cohort of asymptomatic individuals

Variable

No. of cases

Univariable

Multivariable

OR (95% CI)

p Value

OR (95% CI)

p Value

Age, yr

2064

1.056 (1.028–1.086)

< 0.001

1.035 (1.004–1.068)

0.029 *

Male

1120

0.9666 (0.531–1.757)

0.909

  

Height, cm

2064

0.982 (0.954–1.01)

0.212

  

Weight, kg

2064

1.001 (1–1.003)

0.067

  

Body mass index, kg/m2

2064

1.004 (1–1.008)

0.06

1.003 (0.999–1.007)

0.163

Systolic blood pressure, mmHg

2064

1.007 (0.993–1.023)

0.331

  

Diastolic blood pressure, mmHg

2064

1.005 (0.975–1.035)

0.767

  

Heart rate, bpm

2064

1.004 (0.999–1.009)

0.131

  

Hypertension

466

3.078 (1.687–5.618)

< 0.001

2.051 (1.086–3.868)

0.026 *

Coronary artery disease

144

1.148 (0.38–3.468)

0.806

  

Diabetes mellitus

185

1.457 (0.589–3.608)

0.415

  

Hepatitis B carrier

196

2.694 (1.294–5.611)

0.008

2.584 (1.222–5.467)

0.013 *

Hepatitis C

17

4.29 (0.785–23.455)

0.093

2.303 (0.4–13.247)

0.35

Cancer cured for ≥ 5 yrs

51

3.516 (1.138–10.87)

0.029

1.162 (0.35–3.855)

0.806

Surgical history

372

4.991 (2.733–9.114)

< 0.001

3.787 (1.992–7.197)

< 0.001 *

Family history of cancer

863

1.219 (0.67–2.218)

0.517

  
  1. ONCO-RADS = Oncologically Relevant Findings Reporting and Data System; OR = odds ratio
  2. * Statistical significance