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Table 2 Univariable and multivariable analyses in predicting ablation success

From: Correlation between remnant thyroid gland I-131 uptake and serum thyroglobulin levels: can we rely on I-131 whole body scans?

Variable

Univariable analysis

Multivariable analysis

Model 1

Model 2

Model 3

Model 4

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age

1.02 (1.00–1.04)

0.100

        

Sex (vs. male)

0.97 (0.58–1.61)

0.894

        

Pathology

 Primary tumor size (cm)

0.85 (0.66–1.08)

0.189

        

 T3N0-1b (vs. T1a-2N1b)

0.93 (0.46–1.81)

0.823

        

 Thyroiditis present (vs. absent)

0.58 (0.33–0.99)

0.049

0.77 (0.34–1.83)

0.545

0.93 (0.4–2.2)

0.88

0.98 (0.42–2.3)

0.96

0.93 (0.40–2.31)

0.878

Assay at ablation

 Tg (vs. > 4.7 ng/mL)

7.31 (4.20–13.10)

 < 0.001

12.26 (6.49–24.14)

 < 0.001

14.72 (7.31–29.62)

 < 0.001

17.59 (8.28–37.37)

 < 0.001

18.07 (8.77–40.45)

 < 0.001

 TgAb (vs. > 19.2 IU/mL)

5.58 (2.99–10.94)

 < 0.001

8.99 (3.90–22.36)

 < 0.001

8.12 (3.36–19.62)

 < 0.001

7.91 (3.25–19.23)

 < 0.001

7.13 (2.99–18.30)

 < 0.001

I-131 WBS analysis

 Early WBS neck counta (vs. ≤ 51,814)

1.75 (1.09–2.82)

0.022

  

2.16 (1.12–4.2)

0.022

  

1.14 (0.48–2.70)

0.772

 Delayed WBS neck counta (vs. ≤ 4,376)

2.24 (1.46–3.84)

0.003

    

3.59 (1.67–7.74)

 < 0.001

2.93 (1.11–8.05)

0.032

 Reduction ratio (vs. > 95.8) (%)

1.75 (1.07–2.87)

0.027

      

1.61 (0.85–3.07)

0.143

Interval between surgery and ablation (months)

0.98 (0.79–1.24)

0.887

        

AUROC curve (95% CI)

  

0.803 (0.752–0.855)

0.828 (0.779–0.876)

0.842 (0.796–0.888)

0.844 (0.798–0.891)

  1. OR odds ratio, CI confidence interval, Tg thyroglobulin, TgAb thyroglobulin antibody, WBS whole body scan, AUROC area under the receiver operating characteristic
  2. aScan speed adjusted neck count = neck counts/scan speed (mm/sec)