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Table 3 The univariate and multivariate analyses of treatment response in the training set

From: Development and validation of a nomogram model based on pretreatment ultrasound and contrast-enhanced ultrasound to predict the efficacy of neoadjuvant chemotherapy in patients with borderline resectable or locally advanced pancreatic cancer

Imaging characteristics

Univariate analysis

Multivariate analysis

OR

95%CI

P value

OR

95%CI

P value

Location

0.38

0.38–2.42

0.93

 

Tumor size (cm)

0.72

0.50–1.03

0.07

0.81

0.47–1.40

0.45

Nature

0.81

0.26–2.55

0.72

 

MPD dilation (> 4 mm)

1.59

0.59–4.24

0.36

 

Lobulated lesion shape

0.32

0.12–0.87

0.03

0.94

0.22–4.04

0.93

Celiac artery involvement

0.57

0.21–1.58

0.28

 

Taller-than-wide shape in the longitudinal plane

0.17

0.06–0.45

 < 0.001

0.20

0.05–0.72

0.01

Taller-than-wide shape in the cross plane

0.57

0.21–1.58

0.28

 

Blood flow in color doppler

0.96

0.36–2.57

0.94

 

Presence of necrosis

0.34

0.10–1.19

0.09

0.61

0.11–3.72

3.72

Arterial phase (Iso/hypo-enhancement)

1.36

0.55–3.38

0.50

 

Venous phase (Rapid/slow washout)

0.33

0.11–1.03

0.06

0.10

0.01–1.11

0.06

TTP (≤ 25 s/ > 25 s)

8.08

2.90–22.51

 < 0.001

3.64

1.00–13.41

0.05

Peaktumor/Peaknormal

1.69

1.25–2.29

0.001

1.51

1.05–2.17

0.03

Treatment (AG/AS)

1.94

0.78–4.82

0.16

   
  1. MPD Main pancreatic duct, CEUS Contrast-enhanced ultrasound, TTP Time from injection of contrast agent to peak enhancement, Peaktumor/Peaknormal Tumor/surrounding pancreatic parenchyma ratio of enhancement, AG Nab-paclitaxel + gemcitabine, AS Nab-paclitaxel + tegafur