Table 5 Predictive performance of dual-modal ultrasound radiomics nomogram for ACR TI-RADS 4 and 5 thyroid nodules
Variable | Value (95% CI) | ||
|---|---|---|---|
Training cohort (n = 219) | Validation cohort (n = 93) | Entire cohort (n = 312) | |
Cutoff value | 0.524 | 0.524 | 0.524 |
AUC | 0.873 (0.821–0.925) | 0.851 (0.764–0.938) | 0.867 (0.822–0.911) |
Sensitivity, % | 90.2 (85.0-94.78) | 86.4 (77.3–93.9) | 89.0 (84.9–93.2) |
Specificity, % | 69.7 (59.1–80.3) | 66.7 (48.2–81.5) | 68.8 (59.1–78.5) |
PPV, % | 87.3 (82.2–92.5) | 86.4 (78.1–94.6) | 87.1 (82.7–91.5) |
NPV, % | 75.4 (64.6–86.2) | 66.7 (48.9–84.5) | 72.7 (63.4–82.0) |
PLR | 3.552 (2.280–5.534) | 2.623 (1.614–4.264) | 3.104 (2.233–4.315) |
NLR | 0.168 (0.109–0.259) | 0.150 (0.067–0.334) | 0.171 (0.117–0.249) |
Accuracy, % | 84.0 (78.5–88.6) | 80.7 (71.2–88.1) | 83.0 (78.4–87.0) |