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Table 4 Construction of three different models based on risk factors in the training cohort

From: Dual-modal radiomics nomogram based on contrast-enhanced ultrasound to improve differential diagnostic accuracy and reduce unnecessary biopsy rate in ACR TI-RADS 4–5 thyroid nodules

Intercept and variable

Dual-modal US radiomics nomogram

Clinical combined with US model

Dual-modal US Rad-score

Coef

Odds ratio

(95% CI)

P value

Coef

Odds ratio

(95% CI)

P value

Coef

Odds ratio

(95% CI)

P value

Intercept

-0.648

  

0.519

  

-1.475

  

Age

-0.072

0.931 (0.895–0.969)

< 0.001

-0.043

0.958 (0.925–0.992)

0.017

NA

NA

NA

Shape

0.307

1.360 (1.038–1.781)

0.026

0.403

1.496 (1.169–1.913)

0.001

NA

NA

NA

Margin

1.238

3.447 (1.309–9.081)

0.012

NA

NA

NA

NA

NA

NA

Echogenic foci

NA

NA

NA

1.303

3.678 (1.715–7.890)

< 0.001

NA

NA

NA

Enhancement direction

1.012

2.751 (1.147-6.600)

0.023

1.480

4.391 (2.002–9.628)

< 0.001

NA

NA

NA

Ring enhancement

NA

NA

NA

-1.303

0.272 (0.099–0.747)

0.012

NA

NA

NA

BMUS Rad-score

1.098

2.997 (1.386–6.481)

0.005

NA

NA

NA

1.317

3.732 (1.876–7.426)

< 0.001

CEUS Rad-score

1.687

5.405 (2.407–12.135)

< 0.001

NA

NA

NA

1.487

4.422 (2.260–8.652)

< 0.001

  1. Note: US = ultrasound, Rad-score = radiomics score, ACR TI-RADS = American College of Radiology Thyroid Imaging Reporting and Data System, Coef = coefficient, CI = confidence interval, NA = not available, BMUS = B-mode ultrasound, CEUS = contrast-enhanced ultrasound