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Fig. 5 | Cancer Imaging

Fig. 5

From: Dual-modal radiomics nomogram based on contrast-enhanced ultrasound to improve differential diagnostic accuracy and reduce unnecessary biopsy rate in ACR TI-RADS 4–5 thyroid nodules

Fig. 5

Two illustrative examples to present the clinical utilization of the nomogram as diagrams. (A) The blue arrows demonstrated that a 54-year-old patient (point: 10.25) has a thyroid nodule which has an aspect ratio < 1 (point: 0), lobulated margin (point: 11.25), centripetal enhancement direction (point: 9), BMUS radiomics score of 0.354 (point: 23), and CEUS radiomics score of 0.715 (point: 80.5). This thyroid nodule got a total point of 134, corresponding to the malignancy probability (defined as Nomo-score) of 0.339. Therefore, this thyroid nodule was predicted as benign by the nomogram according to the optimal cutoff value of 0.524 and was eventually pathologically confirmed as a nodular goiter. (B) The red arrows showed that a 33-year-old (point: 24) patient has a thyroid nodule which has an aspect ratio > 1 (point: 8), irregular margin (point: 11), centripetal enhancement direction (point: 9), BMUS radiomics score of 1.468 (point: 34.75), and CEUS radiomics score of 1.752 (point: 96.25). This thyroid nodule got a total point of 183, referring to a Nomo-score of 0. 991. The nomogram eventually produced an accurate result consistent with the pathology outcome of papillary thyroid carcinoma. BMUS = B-mode ultrasound, CEUS = contrast-enhanced ultrasound

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