Table 4 Uni- and multivariable logistic regression analyses of factors associated with variceal bleeding using backward elimination in patients with known variceal status at study inclusion (n = 80, n = 13 events)
Patient characteristics | Univariable | Multivariable first step | Multivariable last step | |||
|---|---|---|---|---|---|---|
HR (95%CI) | p-value | aHR (95%CI) | p-value | aHR (95%CI) | p-value | |
Age, per year | 0.90 (0.84–0.98) | 0.008 | 0.88 (0.80–0.97) | 0.013 | 0.90 (0.82–0.98) | 0.022 |
EHS | 0.37 (0.08–1.83) | 0.223 | 0.09 (0.01–1.14) | 0.063 | 0.20 (0.03–1.22) | 0.081 |
ECOG PS, 1 vs. 0 | 2.23 (0.67–7.42) | 0.190 | 9.02 (1.36–59.87) | 0.023 | 5.91 (1.22–28.73) | 0.028 |
CTP score, per point | 0.64 (0.26–1.55) | 0.323 | – | – | – | – |
ALBI score, per point | 1.33 (0.34–5.29) | 0.685 | 0.31 (0.03–2.94) | 0.308 | – | – |
Degree of thrombus-induced vessel occlusion | ||||||
 Partial | 1 | – | 1 | – | – | – |
 Total | 1.07 (0.32–3.51) | 0.915 | 2.79 (0.45–17.44) | 0.274 | – | – |
Thrombus localization | ||||||
 MPV not involved | 1 | – | 1 | – | – | – |
 MPV involved | 0.58 (0.18–1.91) | 0.369 | 3.44 (0.59–20.09) | 0.171 | – | – |
Effective systemic therapy | 0.54 (0.14–2.04) | 0.364 | 0.36 (0.04–3.04) | 0.347 | – | – |
Adequate management of varices | 0.16 (0.04–0.64) | 0.009 | 0.03 (0.00–0.38) | 0.006 | 0.12 (0.02–0.71) | 0.019 |
Therapeutic anticoagulation | 0.82 (0.20–3.31) | 0.777 | 1.73 (0.26–11.62) | 0.574 | – | – |