Table 2 Baseline characteristics for Sonovue group and Sonazoid group
Baseline characteristics for SonoVue (n = 138 tumors) and Sonazoid (n = 110 tumors) | |||
|---|---|---|---|
SonoVue | Sonazoid | P value | |
Sex (M: F) | 105:33 (76.1:23.9) | 82:28 (74.5:25.5) | 0.779 |
Age (year, mean ± SD) | 66.1 ± 8.2 | 66.3 ± 8.7 | 0.563 |
Child-Pugh classification (A/B) | 133/5 | 108/2 | 0.394 |
BCLC stage* | |||
Very early (0) | 95/130 (73.1) | 64/94 (68.1) | 0.494 |
Early (A) | 32/130 (24.6) | 29/94 (30.9) | 0.301 |
Intermediate (B) | 3/130 (2.3) | 1/94 (1.1) | 0.488 |
Tumor location | |||
Left lobe (S2, S3, S4) | 34/138 (24.6) | 28/110 (25.5) | 0.883 |
Right superior segments (S7, S8) | 54/138 (39.1) | 45/110 (40.9) | 0.776 |
Right inferior segments (S5, S6) | 50/138 36.2) | 37/110 (33.6) | 0.670 |
Tumor size (cm, mean ± SD) | 1.5 ± 0.5 | 1.7 ± 0.6 | 0.056 |
Tumor diagnosis | |||
HCC | 129/138 (93.5) | 94/110 (85.5) | 0.054 |
Liver metastasis | 7/138 (5.1) | 16/110 (14.5) | 0.014 |
Other malignancies | 2/138 (1.4) | 0/110 (0) | 0.504 |
Tumor nature | 0.128 | ||
De novo tumor | 32/138 (23.2) | 35/110 (31.8) | |
Recurred tumor | 106/138 (76.8) | 75/110 (68.2) | |
Underlying liver disease | |||
Alcoholic liver disease | 5/138 (3.6) | 3/110 (2.7) | 0.692 |
HBV | 102/138 (73.9) | 75/110 (68.2) | 0.416 |
HCV | 14/138 (10.1) | 7/110 (6.4) | 0.477 |
Others | 17/138 (12.3) | 25/110 (22.7) | 0.045 |
Insertion of artificial ascites | 121/137 (87.7) | 91/110 (82.7) | 0.271 |
Median follow up period (months, range) | 27.5 [0.7–31.3] | 14.9 [0-15.9] | |
Mean procedure time (minutes, range) | 6.8 [2-16.8] | 9.0 [2-22.5] | |